Phenols with Anti-HIV Activity from Daphne acutiloba
Huang, Sheng Zhuo1,4; Zhang, Xing Jie3,4; Li, Xing Yao3,4; Jiang, He Zhong1,4; Ma, Qing Yun2; Wang, Peng Cheng1,4; Liu, Yu Qing1; Hu, Jiang Miao1; Zheng, Yong Tang3; Zhou, Jun1; Zhao, You Xing1,2
2012
发表期刊PLANTA MEDICA
ISSN0032-0943
卷号78期号:2页码:182-185
摘要The present paper describes the study of the phytochemical properties and anti-HIV activity of the phenolic isolates of the plateau medicinal plant Daphne acutiloba Rehd. (Thymelaeceae). Two new lignans named daphnenin (1) and daphnetone (2), along with 11 known ones, were isolated, and their structures were elucidated by 1D and 2D NMR spectroscopy as well as HR-E-SI-MS. In the anti-HIV activity study, daphnenin (1) and caffeic acid n-octadecyl ester (13) showed definite anti-HIV activity with EC50 values of 0.39 and 0.16 mu g/mL, respectively.
关键词Daphne Acutiloba Thymelaeceae Anti-hiv Activity Phenols
资助信息National Nonprofit Institute Research Grant of CATAS-ITBB[110301]; Natural Science Foundation of Yunnan[2008CD159]
学科领域Plant Sciences ; Medicinal ; Chemistry ; Pharmacology & Pharmacy
DOI10.1055/s-0031-1280263
收录类别SCI
语种英语
WOS研究方向Plant Sciences ; Pharmacology & Pharmacy
WOS类目Plant Sciences ; Chemistry, Medicinal ; Pharmacology & Pharmacy
WOS记录号WOS:000299909300014
引用统计
被引频次:11[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.kib.ac.cn/handle/151853/10383
专题植物化学与西部植物资源持续利用国家重点实验室
作者单位1.Chinese Acad Sci, State Key Lab Phytochem & Plant Resources W China, Kunming Inst Bot, Kunming 650204, Peoples R China
2.Chinese Acad Trop Agr Sci, Inst Trop Biosci & Biotechnol, Haikou 571101, Peoples R China
3.Chinese Acad Sci, Kunming Inst Zool, Kunming 650204, Peoples R China
4.Chinese Acad Sci, Grad Sch, Beijing, Peoples R China
推荐引用方式
GB/T 7714
Huang, Sheng Zhuo,Zhang, Xing Jie,Li, Xing Yao,et al. Phenols with Anti-HIV Activity from Daphne acutiloba[J]. PLANTA MEDICA,2012,78(2):182-185.
APA Huang, Sheng Zhuo.,Zhang, Xing Jie.,Li, Xing Yao.,Jiang, He Zhong.,Ma, Qing Yun.,...&Zhao, You Xing.(2012).Phenols with Anti-HIV Activity from Daphne acutiloba.PLANTA MEDICA,78(2),182-185.
MLA Huang, Sheng Zhuo,et al."Phenols with Anti-HIV Activity from Daphne acutiloba".PLANTA MEDICA 78.2(2012):182-185.
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