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题名: Phenols with Anti-HIV Activity from Daphne acutiloba
作者: Huang, Sheng Zhuo1, 4; Zhang, Xing Jie3, 4; Li, Xing Yao3, 4; Jiang, He Zhong1, 4; Ma, Qing Yun2; Wang, Peng Cheng1, 4; Liu, Yu Qing1; Hu, Jiang Miao1; Zheng, Yong Tang3; Zhou, Jun1; Zhao, You Xing1, 2
刊名: PLANTA MEDICA
关键词: Daphne acutiloba ; Thymelaeceae ; anti-HIV activity ; phenols
英文摘要: The present paper describes the study of the phytochemical properties and anti-HIV activity of the phenolic isolates of the plateau medicinal plant Daphne acutiloba Rehd. (Thymelaeceae). Two new lignans named daphnenin (1) and daphnetone (2), along with 11 known ones, were isolated, and their structures were elucidated by 1D and 2D NMR spectroscopy as well as HR-E-SI-MS. In the anti-HIV activity study, daphnenin (1) and caffeic acid n-octadecyl ester (13) showed definite anti-HIV activity with EC50 values of 0.39 and 0.16 mu g/mL, respectively.
出版日期: 2012
卷号: 78, 期号:2, 页码:182-185
DOI标识: 10.1055/s-0031-1280263
语种: 英语
收录类别: SCI
学科分类: Plant Sciences; Chemistry ; Medicinal; Pharmacology & Pharmacy
ISSN号: 0032-0943
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.kib.ac.cn/handle/151853/10383
Appears in Collections:植物化学与西部植物资源持续利用国家重点实验室_期刊论文

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作者单位: 1.Chinese Acad Sci, State Key Lab Phytochem & Plant Resources W China, Kunming Inst Bot, Kunming 650204, Peoples R China
2.Chinese Acad Trop Agr Sci, Inst Trop Biosci & Biotechnol, Haikou 571101, Peoples R China
3.Chinese Acad Sci, Kunming Inst Zool, Kunming 650204, Peoples R China
4.Chinese Acad Sci, Grad Sch, Beijing, Peoples R China

Recommended Citation:
Huang, SZ; Zhang, XJ; Li, XY; Jiang, HZ; Ma, QY; Wang, PC; Liu, YQ; Hu, JM; Zheng, YT; Zhou, J; Zhao, YX.Phenols with Anti-HIV Activity from Daphne acutiloba,PLANTA MEDICA,2012,78(2):182-185
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