A novel antifouling alkaloid from halotolerant fungus Penicillium sp OUCMDZ-776 | |
He, Fei2,3,4; Liu, Zhong5; Yang, Jing6; Fu, Peng1; Peng, Jiang2,3,4; Zhu, Wei-Ming1; Qi, Shu-Hua2,3,4 | |
通讯作者 | Zhu, WM (reprint author), Ocean Univ China, Sch Med & Pharm, Chinese Minist Educ, Key Lab Marine Drugs, Qingdao 266003, Peoples R China, weimingzhu@ouc.edu.cn ; shuhuaqi@scsio.ac.cn |
2012-05-02 | |
发表期刊 | TETRAHEDRON LETTERS |
ISSN | 0040-4039 |
卷号 | 53期号:18页码:2280-2283 |
摘要 | Penispirolloid A (1), a novel alkaloid possessing a unique Spiro imidazolidinyl skeleton, was isolated from a halotolerant fungal strain. Penicillium sp. OUCMDZ-776. Its structure was elucidated on the basis of spectroscopic methods and quantum chemical CD calculation. Compound 1 showed significant antifouling activity toward Bugula neritina larvae with EC50 of 2.40 mu g/ml. Plausible biogenesis of compound 1 was also proposed. (C) 2012 Elsevier Ltd. All rights reserved. |
关键词 | Penicillium Sp. Alkaloids Antifouling |
学科领域 | Chemistry ; Organic |
DOI | 10.1016/j.tetlet.2012.02.063 |
收录类别 | SCI ; IC |
语种 | 英语 |
WOS记录号 | WOS:000303032300004 |
引用统计 | |
文献类型 | 期刊论文 |
条目标识符 | http://ir.kib.ac.cn/handle/151853/10371 |
专题 | 植物化学与西部植物资源持续利用国家重点实验室 |
作者单位 | 1.Ocean Univ China, Sch Med & Pharm, Chinese Minist Educ, Key Lab Marine Drugs, Qingdao 266003, Peoples R China 2.Chinese Acad Sci, S China Sea Inst Oceanol, Key Lab Marine Bioresources Sustainable Utilizat, Guangzhou 510301, Guangdong, Peoples R China 3.Chinese Acad Sci, S China Sea Inst Oceanol, RNAM Ctr Marine Microbiol, Guangzhou 510301, Guangdong, Peoples R China 4.Chinese Acad Sci, S China Sea Inst Oceanol, Guangdong Key Lab Marine Mat Med, Guangzhou 510301, Guangdong, Peoples R China 5.Jinan Univ, Natl Engn Res Ctr Genet Med, Guangdong Prov Key Lab Bioengn Med, Guangzhoujinan Biomed Res & Dev Ctr, Guangzhou 510632, Guangdong, Peoples R China 6.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650204, Peoples R China |
推荐引用方式 GB/T 7714 | He, Fei,Liu, Zhong,Yang, Jing,et al. A novel antifouling alkaloid from halotolerant fungus Penicillium sp OUCMDZ-776[J]. TETRAHEDRON LETTERS,2012,53(18):2280-2283. |
APA | He, Fei.,Liu, Zhong.,Yang, Jing.,Fu, Peng.,Peng, Jiang.,...&Qi, Shu-Hua.(2012).A novel antifouling alkaloid from halotolerant fungus Penicillium sp OUCMDZ-776.TETRAHEDRON LETTERS,53(18),2280-2283. |
MLA | He, Fei,et al."A novel antifouling alkaloid from halotolerant fungus Penicillium sp OUCMDZ-776".TETRAHEDRON LETTERS 53.18(2012):2280-2283. |
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