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题名: A novel antifouling alkaloid from halotolerant fungus Penicillium sp OUCMDZ-776
作者: He, Fei2, 3, 4; Liu, Zhong5; Yang, Jing6; Fu, Peng1; Peng, Jiang2, 3, 4; Zhu, Wei-Ming1; Qi, Shu-Hua2, 3, 4
刊名: TETRAHEDRON LETTERS
关键词: Penicillium sp. ; Alkaloids ; Antifouling
英文摘要: Penispirolloid A (1), a novel alkaloid possessing a unique Spiro imidazolidinyl skeleton, was isolated from a halotolerant fungal strain. Penicillium sp. OUCMDZ-776. Its structure was elucidated on the basis of spectroscopic methods and quantum chemical CD calculation. Compound 1 showed significant antifouling activity toward Bugula neritina larvae with EC50 of 2.40 mu g/ml. Plausible biogenesis of compound 1 was also proposed. (C) 2012 Elsevier Ltd. All rights reserved.
出版日期: 2012-05-02
卷号: 53, 期号:18, 页码:2280-2283
DOI标识: 10.1016/j.tetlet.2012.02.063
语种: 英语
收录类别: SCI ; IC
学科分类: Chemistry ; Organic
ISSN号: 0040-4039
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.kib.ac.cn/handle/151853/10371
Appears in Collections:植物化学与西部植物资源持续利用国家重点实验室_期刊论文

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作者单位: 1.Ocean Univ China, Sch Med & Pharm, Chinese Minist Educ, Key Lab Marine Drugs, Qingdao 266003, Peoples R China
2.Chinese Acad Sci, S China Sea Inst Oceanol, Key Lab Marine Bioresources Sustainable Utilizat, Guangzhou 510301, Guangdong, Peoples R China
3.Chinese Acad Sci, S China Sea Inst Oceanol, RNAM Ctr Marine Microbiol, Guangzhou 510301, Guangdong, Peoples R China
4.Chinese Acad Sci, S China Sea Inst Oceanol, Guangdong Key Lab Marine Mat Med, Guangzhou 510301, Guangdong, Peoples R China
5.Jinan Univ, Natl Engn Res Ctr Genet Med, Guangdong Prov Key Lab Bioengn Med, Guangzhoujinan Biomed Res & Dev Ctr, Guangzhou 510632, Guangdong, Peoples R China
6.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650204, Peoples R China

Recommended Citation:
He, F; Liu, Z; Yang, J; Fu, P; Peng, J; Zhu, WM; Qi, SH.A novel antifouling alkaloid from halotolerant fungus Penicillium sp OUCMDZ-776,TETRAHEDRON LETTERS,2012,53(18):2280-2283
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