A novel antifouling alkaloid from halotolerant fungus Penicillium sp OUCMDZ-776
He, Fei2,3,4; Liu, Zhong5; Yang, Jing6; Fu, Peng1; Peng, Jiang2,3,4; Zhu, Wei-Ming1; Qi, Shu-Hua2,3,4
2012-05-02
发表期刊TETRAHEDRON LETTERS
ISSN0040-4039
卷号53期号:18页码:2280-2283
摘要Penispirolloid A (1), a novel alkaloid possessing a unique Spiro imidazolidinyl skeleton, was isolated from a halotolerant fungal strain. Penicillium sp. OUCMDZ-776. Its structure was elucidated on the basis of spectroscopic methods and quantum chemical CD calculation. Compound 1 showed significant antifouling activity toward Bugula neritina larvae with EC50 of 2.40 mu g/ml. Plausible biogenesis of compound 1 was also proposed. (C) 2012 Elsevier Ltd. All rights reserved.
关键词Penicillium Sp. Alkaloids Antifouling
资助信息National Basic Research Program of China[2010CB833803]; National Natural Science Foundation of China[40931160435, 40976090, 20872151]; Chinese Academy of Science[KSCX2-EW-G-12B, 5060267]
学科领域Chemistry ; Organic
DOI10.1016/j.tetlet.2012.02.063
收录类别SCI ; IC
语种英语
WOS研究方向Chemistry
WOS类目Chemistry, Organic
WOS记录号WOS:000303032300004
引用统计
被引频次:16[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.kib.ac.cn/handle/151853/10371
专题植物化学与西部植物资源持续利用国家重点实验室
作者单位1.Ocean Univ China, Sch Med & Pharm, Chinese Minist Educ, Key Lab Marine Drugs, Qingdao 266003, Peoples R China
2.Chinese Acad Sci, S China Sea Inst Oceanol, Key Lab Marine Bioresources Sustainable Utilizat, Guangzhou 510301, Guangdong, Peoples R China
3.Chinese Acad Sci, S China Sea Inst Oceanol, RNAM Ctr Marine Microbiol, Guangzhou 510301, Guangdong, Peoples R China
4.Chinese Acad Sci, S China Sea Inst Oceanol, Guangdong Key Lab Marine Mat Med, Guangzhou 510301, Guangdong, Peoples R China
5.Jinan Univ, Natl Engn Res Ctr Genet Med, Guangdong Prov Key Lab Bioengn Med, Guangzhoujinan Biomed Res & Dev Ctr, Guangzhou 510632, Guangdong, Peoples R China
6.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650204, Peoples R China
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He, Fei,Liu, Zhong,Yang, Jing,et al. A novel antifouling alkaloid from halotolerant fungus Penicillium sp OUCMDZ-776[J]. TETRAHEDRON LETTERS,2012,53(18):2280-2283.
APA He, Fei.,Liu, Zhong.,Yang, Jing.,Fu, Peng.,Peng, Jiang.,...&Qi, Shu-Hua.(2012).A novel antifouling alkaloid from halotolerant fungus Penicillium sp OUCMDZ-776.TETRAHEDRON LETTERS,53(18),2280-2283.
MLA He, Fei,et al."A novel antifouling alkaloid from halotolerant fungus Penicillium sp OUCMDZ-776".TETRAHEDRON LETTERS 53.18(2012):2280-2283.
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