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Hydrogen peroxide/ATR-Chk2 activation mediates p53 protein stabilization and anti-cancer activity of cheliensisin A in human cancer cells 期刊论文
ONCOTARGET, 2014, 卷号: 5, 期号: 3, 页码: 841-852
Authors:  Zhang, Jingjie;  Gao, Guangxun;  Chen, Liang;  Li, Jingxia;  Deng, Xu;  Zhao, Qin-shi;  Huang, Chuanshu
View  |  Adobe PDF(3282Kb)  |  Favorite  |  View/Download:216/33  |  Submit date:2014/05/16
Cheliensisin a  Apoptosis  Colon Cancer  P53  Chemotherapeutic Agent  
Cheliensisin A Inhibits EGF-Induced Cell Transformation with Stabilization of p53 Protein Via a Hydrogen Peroxide/Chk1-Dependent Axis 期刊论文
CANCER PREVENTION RESEARCH, 2013, 卷号: 6, 期号: 9, 页码: 949-958
Authors:  Zhang, Jingjie;  Gao, Guangxun;  Chen, Liang;  Deng, Xu;  Li, Jingxia;  Yu, Yonghui;  Zhang, Dongyun;  Li, Fei;  Zhang, Min;  Zhao, Qinshi;  Huang, Chuanshu
View  |  Adobe PDF(1677Kb)  |  Favorite  |  View/Download:2006/184  |  Submit date:2013/10/16
Dna-damage  Cancer Chemoprevention  Induced Phosphorylation  Activation  Apoptosis  Expression  Induction  Hyperoxia  Therapy  Roles  
三种天然产物的构效关系研究和毛萼乙素、Vibsanin B分子探针的合成 学位论文
: 中国科学院研究生院, 2012
Authors:  邓旭
Adobe PDF(5731Kb)  |  Favorite  |  View/Download:442/35  |  Submit date:2015/03/23
景洪哥纳香甲素  丹参酮  对映贝壳杉烷型二萜  毛萼乙素  Vibsanin b  Serratamine a 和b  活性  构效关系  标记物  靶点发现  全合成