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Discovery of 2-(Methylcarbonylamino) thiazole as PDE4 inhibitors via virtual screening and biological evaluation 期刊论文
JOURNAL OF MOLECULAR GRAPHICS & MODELLING, 2023, 卷号: 124, 页码: 108567
作者:  Ma,Rui;  Song,Na;  Wang,Lveli;  Gu,Xi;  Xiong,Feng;  Zhang,Shuqun;  Zhang,Jie;  Yang,Weimin;  Zuo,Zhili
浏览  |  Adobe PDF(5778Kb)  |  收藏  |  浏览/下载:33/13  |  提交时间:2024/07/22
PHOSPHODIESTERASE-4 INHIBITOR  ACCURATE DOCKING  APREMILAST  EFFICACY  INSIGHTS  DISEASE  ASTHMA  POTENT  GLIDE  
Discovery of a potent and selective adenylyl cyclase type 8 agonist by docking-based virtual screening 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2020, 卷号: 30, 期号: 2, 页码: 7
作者:  Weng, Zhiying;  Xu, Guowei;  Chen, Dingyuan;  Yang, Yaqing;  Song, Gao;  Shen, Wen;  Zhang, Shuqun;  Wang, LiangLiang;  Yang, Weimin;  Zuo, Zhili
收藏  |  浏览/下载:229/0  |  提交时间:2020/03/18
Adenylyl cyclases  Homology modeling  Consensus scoring  Molecular dynamics simulation  Virtual screening  Biological evaluation  
The discovery, design and synthesis of potent agonists of adenylyl cyclase type 2 by virtual screening combining biological evaluation 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2020
作者:  Xu, Guowei;  Yang, Yaqing;  Yang, Yanming;  Song, Gao;  Li, Shanshan;  Zhang, Jiajun;  Yang, Weimin;  Wang, Liang-Liang;  Weng, Zhiying;  Zuo, Zhili
浏览  |  Adobe PDF(2526Kb)  |  收藏  |  浏览/下载:171/38  |  提交时间:2021/01/05
Isoforskolin pretreatment attenuates lipopolysaccharide-induced acute lung injury in animal models 期刊论文
INTERNATIONAL IMMUNOPHARMACOLOGY, 2011, 卷号: 11, 期号: 6, 页码: 683-692
作者:  Yang, Weimin;  Qiang, Dongjin;  Zhang, Min;  Ma, Limei;  Zhang, Yonghui;  Qing, Chen;  Xu, Yunlong;  Zhen, Chunlan;  Liu, Jikai;  Chen, Yan-Hua
Adobe PDF(2189Kb)  |  收藏  |  浏览/下载:496/164  |  提交时间:2012/04/10
Acute Lung Injury  Isoforskolin  Lipopolysaccharide  Inflammation  Cytokine  
1-氢-2-吲哚酮-3-苄基/取代苄基-3-甲酸酯类化合物的新用途 专利
公开日期: 2018-06-01
发明人:  翁稚颖;  左之利;  杨为民;  张树群;  沈雯;  汪亮亮;  宋杲;  杨雅清;  徐国伟
收藏  |  浏览/下载:158/0  |  提交时间:2018/10/24