Gelselegine-gelsedine type bisindoles as well as the units from Gelsemium elegans with promoting proliferation of oral mucosa fibroblast cells

doi:10.1016/j.phytochem.2024.114077

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	Gelselegine-gelsedine type bisindoles as well as the units from Gelsemium elegans with promoting proliferation of oral mucosa fibroblast cells
	Lin, Jing; Wu, Jing; Bao, Mei-Fen; Kongkiatpaiboon, Sumet; Cai, Xiang-Hai
	2024
发表期刊	PHYTOCHEMISTRY
ISSN	0031-9422
卷号	222 页码:114077
摘要	Two undescribed bisindole alkaloids, gelseginedine A (1) and its rearranged gelseginedine B (2), and seven unreported gelselegine-type oxindole alkaloids (3-9) were isolated from the stems and leaves of Gelsemium elegans, together with five known alkaloids (10-14). Compounds 1 and 2 represented the first examples of gelselegine-gelsedine type alkaloids which bridged two units by a double bond. Their structures with absolute configurations were elucidated by means of HRESIMS, NMR and calculational chemistry. The performed bioassay revealed that 14 could promote the proliferation of human oral mucosa fibroblast cells.
DOI	10.1016/j.phytochem.2024.114077
WOS记录号	WOS:001231671000001
引用统计	被引频次：3[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.kib.ac.cn/handle/151853/76319
专题	中国科学院昆明植物研究所
推荐引用方式 GB/T 7714	Lin, Jing,Wu, Jing,Bao, Mei-Fen,et al. Gelselegine-gelsedine type bisindoles as well as the units from Gelsemium elegans with promoting proliferation of oral mucosa fibroblast cells[J]. PHYTOCHEMISTRY,2024,222:114077.
APA	Lin, Jing,Wu, Jing,Bao, Mei-Fen,Kongkiatpaiboon, Sumet,&Cai, Xiang-Hai.(2024).Gelselegine-gelsedine type bisindoles as well as the units from Gelsemium elegans with promoting proliferation of oral mucosa fibroblast cells.PHYTOCHEMISTRY,222,114077.
MLA	Lin, Jing,et al."Gelselegine-gelsedine type bisindoles as well as the units from Gelsemium elegans with promoting proliferation of oral mucosa fibroblast cells".PHYTOCHEMISTRY 222(2024):114077.

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