Five quinolizidine alkaloids with anti-tobacco mosaic virus activities from two species of Sophora

doi:10.1016/j.cclet.2023.108927

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	Five quinolizidine alkaloids with anti-tobacco mosaic virus activities from two species of Sophora
	Zhang, Ji; Zhang, Tong; An, Qiao; Zhang, Peng; Tian, Cai-Yan; Yi, Ping; Hu, Zhan-Xing; Hao, Xiao-Jiang
	2024
发表期刊	CHINESE CHEMICAL LETTERS
ISSN	1001-8417
卷号	35 期号:6 页码:108927
摘要	Three novel matrine-type alkaloids ( 1 - 3 ) and two unprecedented aloperine-type alkaloids ( 4 and 5 ) were isolated from the root of Sophora tonkinensis and the seeds of Sophora alopecuroides respectively. Notably, compound 1 possessed an unprecedented 6/5/6 tricyclic skeleton, while compounds 2 and 3 characterized by rare 6/6/5/6 tetracyclic system and 6/6/6/6/6 pentacyclic system respectively. Moreover, compound 4 possessed an unprecedented 6/7/6/6 tetracyclic core, and compound 5 characterized by rare 6/6/6/6 tetracyclic skeleton. Their structures were elucidated by comprehensive spectroscopic data analysis and electronic circular dichroism (ECD) calculations. Biological tests indicated that compound 5 displayed significant anti -tobacco mosaic virus (TMV) activity compared with the positive control ningnanmycin. (c) 2024 Published by Elsevier B.V. on behalf of Chinese Chemical Society and Institute of Materia Medica, Chinese Academy of Medical Sciences.
DOI	10.1016/j.cclet.2023.108927
WOS记录号	WOS:001216912300001
引用统计	被引频次：3[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.kib.ac.cn/handle/151853/76301
专题	中国科学院昆明植物研究所
推荐引用方式 GB/T 7714	Zhang, Ji,Zhang, Tong,An, Qiao,et al. Five quinolizidine alkaloids with anti-tobacco mosaic virus activities from two species of Sophora[J]. CHINESE CHEMICAL LETTERS,2024,35(6):108927.
APA	Zhang, Ji.,Zhang, Tong.,An, Qiao.,Zhang, Peng.,Tian, Cai-Yan.,...&Hao, Xiao-Jiang.(2024).Five quinolizidine alkaloids with anti-tobacco mosaic virus activities from two species of Sophora.CHINESE CHEMICAL LETTERS,35(6),108927.
MLA	Zhang, Ji,et al."Five quinolizidine alkaloids with anti-tobacco mosaic virus activities from two species of Sophora".CHINESE CHEMICAL LETTERS 35.6(2024):108927.

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