A haplotype-resolved genome assembly of Coptis teeta, an endangered plant of significant medicinal value

doi:10.1038/s41597-024-03861-5

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	A haplotype-resolved genome assembly of Coptis teeta, an endangered plant of significant medicinal value
	Wang, Ya; Liu, Yan; Miao, Ke; Hou, Luxiao; Guo, Xiaorong; Ji, Yunheng
	2024
发表期刊	SCIENTIFIC DATA
卷号	11 期号:1 页码:1012
摘要	Coptis teeta Wall. (Ranunculaceae), an endangered plant species of significant medicinal value, predominantly undergoes clonal propagation, potentially compromising the species' evolutionary potential and ultimately increase its risk of extinction. In this study, we successfully assembled two sets of haploid genomes (Hap1 and Hap2) for C. teeta, comprising nine homologous chromosome pairs, by employing Illumina and PacBio sequencing technologies. The genome annotation identified a total of 43,979 and 46,311 protein-coding genes in Hap1 and in Hap2, and most of them were functionally annotated. The high-quality reference genome will serve as an indispensable genomic resource for conservation and comprehensive exploitation of this endangered species. Between the two haploid genomes, numerous structural alterations were detected within the nine homologous chromosome pairs, potentially resulting in aberrant synapsis and irregular chromosomal segregation and thus contributing to the sustained preservation of clonal propagation in C. teeta. The findings offer new perspective for elucidating the genetic mechanism underlying the compromised sexual reproductive capacity of C. teeta, thereby facilitating its enhancement though molecular breeding and genetic improvement.
DOI	10.1038/s41597-024-03861-5
WOS记录号	WOS:001315824700005
引用统计
文献类型	期刊论文
条目标识符	http://ir.kib.ac.cn/handle/151853/75981
专题	中国科学院昆明植物研究所
推荐引用方式 GB/T 7714	Wang, Ya,Liu, Yan,Miao, Ke,et al. A haplotype-resolved genome assembly of Coptis teeta, an endangered plant of significant medicinal value[J]. SCIENTIFIC DATA,2024,11(1):1012.
APA	Wang, Ya,Liu, Yan,Miao, Ke,Hou, Luxiao,Guo, Xiaorong,&Ji, Yunheng.(2024).A haplotype-resolved genome assembly of Coptis teeta, an endangered plant of significant medicinal value.SCIENTIFIC DATA,11(1),1012.
MLA	Wang, Ya,et al."A haplotype-resolved genome assembly of Coptis teeta, an endangered plant of significant medicinal value".SCIENTIFIC DATA 11.1(2024):1012.

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