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Meroterpenoids from Ganoderma petchii inhibiting migration of triple negative breast cancer cells
Zhang,Jiao-Jiao; Guo,Ping-Xia; Yang,Zhong-Hui; Cai,Dan; Dai,Wei-Feng; Lu,Qing; Cheng,Yong-Xian
2023
发表期刊FITOTERAPIA
ISSN1873-6971
卷号167页码:105505
摘要Ganoderpetchoids A-E and (-)-dayaolingzhiol H, six undescribed meroterpenoids, were isolated from Ganoderma petchii. Their structures including the relative configurations were identified by means of spectroscopic methods and 13C NMR calculations. Chiral separation of the new racemics was performed to afford their respective enantiomers. The absolute configurations of the new isolates were clarified by computational approaches, CD comparisons and X-ray diffraction analysis. Biological studies toward triple negative breast cancer indicated that (+)-6 and (-)-6 significantly inhibit the migration of MDA-MB-231 cell line.
关键词Ganoderma petchii Meroterpenoids Triple negative breast cancer Cell migration
学科领域Pharmacology & Pharmacy
DOI10.1016/j.fitote.2023.105505
收录类别SCI
WOS记录号WOS:000984899200001
引用统计
文献类型期刊论文
条目标识符http://ir.kib.ac.cn/handle/151853/75511
专题中国科学院昆明植物研究所
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Zhang,Jiao-Jiao,Guo,Ping-Xia,Yang,Zhong-Hui,et al. Meroterpenoids from Ganoderma petchii inhibiting migration of triple negative breast cancer cells[J]. FITOTERAPIA,2023,167:105505.
APA Zhang,Jiao-Jiao.,Guo,Ping-Xia.,Yang,Zhong-Hui.,Cai,Dan.,Dai,Wei-Feng.,...&Cheng,Yong-Xian.(2023).Meroterpenoids from Ganoderma petchii inhibiting migration of triple negative breast cancer cells.FITOTERAPIA,167,105505.
MLA Zhang,Jiao-Jiao,et al."Meroterpenoids from Ganoderma petchii inhibiting migration of triple negative breast cancer cells".FITOTERAPIA 167(2023):105505.
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