Diverse aspidosperma-type alkaloids from the leaves of Tabernaemontana bovina with anti-hepatoma activity

doi:10.1016/j.fitote.2023.105588

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	Diverse aspidosperma-type alkaloids from the leaves of Tabernaemontana bovina with anti-hepatoma activity
	Yu,Yang; Wu,Jing; Bao,Mei-Fen; Schinnerl,Johann; Cai,Xiang-Hai
	2023
发表期刊	FITOTERAPIA
ISSN	1873-6971
卷号	169 页码:105588
摘要	Seventeen undescribed Aspidosperma-type alkaloids (ASPs), along with nine known ones were isolated from the leaves of Tabernaemontana bovina. Taberbovermines A and B were assigned to tabersonine-type with a contracted A-and E-ring, respectively. Taberbovermine C was attributed to tabersonine without D ring. These structures of the ASPs were established on the basis of comprehensive spectroscopic data, electronic circular dichroism cal-culations and X-ray diffraction. The summaries of structure-activity relationship of tabersonine class were dis-cussed based on hepatoma cells screening.
关键词	Tabernaemontana bovina Apocynaceae Aspidosperma alkaloids Taberbovermines Hepatom Structure -activity relationship BISINDOLE ALKALOIDS INDOLE ALKALOIDS LEUCONOXINE
DOI	10.1016/j.fitote.2023.105588
收录类别	SCI
WOS记录号	WOS:001034731300001
引用统计
文献类型	期刊论文
条目标识符	http://ir.kib.ac.cn/handle/151853/75509
专题	中国科学院昆明植物研究所
推荐引用方式 GB/T 7714	Yu,Yang,Wu,Jing,Bao,Mei-Fen,et al. Diverse aspidosperma-type alkaloids from the leaves of Tabernaemontana bovina with anti-hepatoma activity[J]. FITOTERAPIA,2023,169:105588.
APA	Yu,Yang,Wu,Jing,Bao,Mei-Fen,Schinnerl,Johann,&Cai,Xiang-Hai.(2023).Diverse aspidosperma-type alkaloids from the leaves of Tabernaemontana bovina with anti-hepatoma activity.FITOTERAPIA,169,105588.
MLA	Yu,Yang,et al."Diverse aspidosperma-type alkaloids from the leaves of Tabernaemontana bovina with anti-hepatoma activity".FITOTERAPIA 169(2023):105588.

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