Three New Constituents with Anti-Inflammatory and Antimicrobial Activities in Vitro from the Roots of Capsicum annuum L.

doi:10.1002/cbdv.202300691

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	Three New Constituents with Anti-Inflammatory and Antimicrobial Activities in Vitro from the Roots of Capsicum annuum L.
	Shi,Jiang; Deng,Lu-Lu; Li,Jiang; Wang,Min; Fan,Yan-Hua; Pan,Wei-Dong; Hao,Xiao-Jiang; Mu,Shu-Zhen
	2023
发表期刊	CHEMISTRY & BIODIVERSITY
ISSN	1612-1880
卷号	20 期号:8
摘要	Three new compounds, including two new sesquiterpenes (1-2), named Annuumine E-F, and one new natural product, 3-hydroxy-2,6-dimethylbenzenemethanol (3), together with seventeen known compounds (4-20) were isolated from the ethanol extract of the roots of Capsicum annuum L. Among them, five compounds (4, 5, 9, 10 and 20) were isolated from this plant for the first time. The structures of new compounds (1-3) were determined via detailed analysis of the IR, HR-ESI-MS and 1D and 2D NMR spectra. The anti-inflammatory activities of the isolated compounds were evaluated by their ability to reduce NO release by LPS-induced RAW 264.7 cells. Notably, compound 11 exhibited moderate anti-inflammatory activity (IC50=21.11 & mu;M). Moreover, the antibacterial activities of the isolated compounds were also evaluated.
关键词	anti-inflammatory active constituent roots of Capsicum annuum L sesquiterpenes structural identification AGRICULTURAL WASTE SESQUITERPENOIDS
DOI	10.1002/cbdv.202300691
收录类别	SCI
WOS记录号	WOS:001034829900001
引用统计
文献类型	期刊论文
条目标识符	http://ir.kib.ac.cn/handle/151853/75324
专题	中国科学院昆明植物研究所
推荐引用方式 GB/T 7714	Shi,Jiang,Deng,Lu-Lu,Li,Jiang,et al. Three New Constituents with Anti-Inflammatory and Antimicrobial Activities in Vitro from the Roots of Capsicum annuum L.[J]. CHEMISTRY & BIODIVERSITY,2023,20(8).
APA	Shi,Jiang.,Deng,Lu-Lu.,Li,Jiang.,Wang,Min.,Fan,Yan-Hua.,...&Mu,Shu-Zhen.(2023).Three New Constituents with Anti-Inflammatory and Antimicrobial Activities in Vitro from the Roots of Capsicum annuum L..CHEMISTRY & BIODIVERSITY,20(8).
MLA	Shi,Jiang,et al."Three New Constituents with Anti-Inflammatory and Antimicrobial Activities in Vitro from the Roots of Capsicum annuum L.".CHEMISTRY & BIODIVERSITY 20.8(2023).

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