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Isolation and biosynthesis of daturamycins from Streptomyces sp. KIB-H1544
Chen, Yin; Ren, Jinqiu; Yang, Ruimin; Li, Jie; Huang, Sheng-Xiong; Yan, Yijun
2022
发表期刊BEILSTEIN JOURNAL OF ORGANIC CHEMISTRY
卷号18页码:1009-1016
摘要Two novel diarylcyclopentenones daturamycin A and B (1 and 2), and one new p-terphenyl daturamycin C (3), along with three known congeners (4-6), were isolated from a rhizosphere soil-derived Streptomyces sp. KIB-H1544. The structures of new com-pounds were elucidated via a joint use of spectroscopic analyses and single-crystal X-ray diffractions. Compounds 1 and 2 belong to a rare class of tricyclic 6/5/6 diarylcyclopentenones, and compounds 3-6 possess a C-18 tricyclic aromatic skeleton. The biosyn-thetic gene cluster of daturamycins was identified through gene knockout and biochemical characterization experiments and the biosynthetic pathway of daturamycins was proposed.
关键词biosynthesis diarylcyclopentenone polyporic acid synthetase p-terphenyl Streptomyces P-TERPHENYLS METABOLITES DIVERSITY INVOLUTIN
DOI10.3762/bjoc.18.101
收录类别SCI
WOS记录号WOS:000856837900001
引用统计
文献类型期刊论文
条目标识符http://ir.kib.ac.cn/handle/151853/74695
专题中国科学院昆明植物研究所
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GB/T 7714
Chen, Yin,Ren, Jinqiu,Yang, Ruimin,et al. Isolation and biosynthesis of daturamycins from Streptomyces sp. KIB-H1544[J]. BEILSTEIN JOURNAL OF ORGANIC CHEMISTRY,2022,18:1009-1016.
APA Chen, Yin,Ren, Jinqiu,Yang, Ruimin,Li, Jie,Huang, Sheng-Xiong,&Yan, Yijun.(2022).Isolation and biosynthesis of daturamycins from Streptomyces sp. KIB-H1544.BEILSTEIN JOURNAL OF ORGANIC CHEMISTRY,18,1009-1016.
MLA Chen, Yin,et al."Isolation and biosynthesis of daturamycins from Streptomyces sp. KIB-H1544".BEILSTEIN JOURNAL OF ORGANIC CHEMISTRY 18(2022):1009-1016.
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