Colored Dimeric Alkaloids from the Barks of Erythrina variegata and Their Neuroprotective Effects

doi:10.1021/acs.joc.1c01489

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	Colored Dimeric Alkaloids from the Barks of Erythrina variegata and Their Neuroprotective Effects
	Tang,Yu-Ting ; Wu,Jing ; Yu,Yang ; Bao,Mei-Fen ; Tan,Qin-Gang ; Schinnerl,Johann ; Cai,Xiang-Hai
	2021
发表期刊	JOURNAL OF ORGANIC CHEMISTRY
ISSN	0022-3263
卷号	86 期号:19 页码:13381-13387
摘要	Five dimeric Erythrina alkaloids, named erythrivarines J-N, were isolated from the barks of Erythrina variegata L. (Fabaceae). The erythrivarines J-L featured a 6/6/5/6/6/5/6/6/6 ring system and super conjugated double bond systems, causing intense color from blue to wine red, while erythrivarines M-N looked orange. The structures of the isolated compounds were elucidated by 1D and 2D NMR experiments combined with MS and confirmed by the X-ray crystal diffraction technique. The performed bioassay using HEI-OC-1 cells revealed neuroprotective properties of erythrivarine N against the hearing loss causing antibiotics, neomycin.
DOI	10.1021/acs.joc.1c01489
WOS记录号	WOS:000704707200016
引用统计
文献类型	期刊论文
条目标识符	http://ir.kib.ac.cn/handle/151853/73775
专题	中国科学院昆明植物研究所
作者单位	1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Yunnan, Peoples R China 2.Guilin Med Univ, Coll Med, Guilin 541199, Peoples R China 3.Univ Vienna, Dept Bot & Biodivers Res, A-1030 Vienna, Austria
推荐引用方式 GB/T 7714	Tang,Yu-Ting,Wu,Jing,Yu,Yang,et al. Colored Dimeric Alkaloids from the Barks of Erythrina variegata and Their Neuroprotective Effects[J]. JOURNAL OF ORGANIC CHEMISTRY,2021,86(19):13381-13387.
APA	Tang,Yu-Ting.,Wu,Jing.,Yu,Yang.,Bao,Mei-Fen.,Tan,Qin-Gang.,...&Cai,Xiang-Hai.(2021).Colored Dimeric Alkaloids from the Barks of Erythrina variegata and Their Neuroprotective Effects.JOURNAL OF ORGANIC CHEMISTRY,86(19),13381-13387.
MLA	Tang,Yu-Ting,et al."Colored Dimeric Alkaloids from the Barks of Erythrina variegata and Their Neuroprotective Effects".JOURNAL OF ORGANIC CHEMISTRY 86.19(2021):13381-13387.

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