A specific and bioactive polysaccharide marker for Cordyceps

doi:10.1016/j.carbpol.2021.118343

KIB OpenIR

	A specific and bioactive polysaccharide marker for Cordyceps
	Li,Li-Feng ; But,Grace Wing-Chiu ; Zhang,Quan-Wei ; Liu,Man ; Chen,Miao-Miao ; Wen,Xin ; Wu,Hoi-Yan ; Cheng,Hui-Yuan ; Puno,Pema-Tenzin ; Zhang,Ji-Xia ; Fung,Hau-Yee ; Bai,Su-Ping ; Wong,Tin-Long ; Zhao,Zhong-Zhen ; Cao,Hui ; Tsim,Karl Wah-Keung ; Shaw,Pang-Chui ; Han,Quan-Bin ; Sun,Han-Dong
	2021
发表期刊	CARBOHYDRATE POLYMERS
ISSN	0144-8617
卷号	269 页码:118343
摘要	Cordyceps is one of the most expensive and widely used functional foods. But the authenticity is still a concern due to the lack of appropriate markers. By targeting polysaccharides, this study aimed to develop a specific, and bioactive marker for Cordyceps. Firstly, the results of screening tests of 250 samples by examining both genetic markers and polysaccharide profile showed that a unique polysaccharide fraction (named CCP) was particular to the caterpillar parts. Its potential as a marker was further demonstrated by its ability to induce NO and cytokine production in RAW 264.7 cells. CCP was characterized to be an alpha-1,4-glucan with a branch at C-6 by the conventional structure analyzing and de novo oligosaccharides sequencing. The content of CCP was closely correlated to the traditional classification criteria. Generally, CCP was a marker that simultaneously enables qualitative and quantitative analysis of Cordyceps.
关键词	Cordyceps Polysaccharide Marker Authentication Immune activity STRUCTURAL-ANALYSIS SINENSIS AUTHENTICATION MACROPHAGES SEQUENCE
DOI	10.1016/j.carbpol.2021.118343
WOS记录号	WOS:000678037400007
引用统计	被引频次：12[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.kib.ac.cn/handle/151853/73322
专题	中国科学院昆明植物研究所
作者单位	1.Hong Kong Baptist Univ, Sch Chinese Med, Hong Kong, Peoples R China 2.Chinese Univ Hong Kong, Sch Life Sci, Hong Kong, Peoples R China 3.Chinese Univ Hong Kong, Li Dak Sum Yip Yio Chin R & Ctr Chinese Med, Hong Kong, Peoples R China 4.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources We, Kunming, Yunnan, Peoples R China 5.Xinxiang Med Univ, Sch Pharm, Xinxiang, Henan, Peoples R China 6.Jinan Univ, Sch Pharm, Guangzhou, Peoples R China 7.Hong Kong Univ Sci & Technol, Div Life Sci, Hong Kong, Peoples R China 8.Chinese Univ Hong Kong, Inst Chinese Med, Hong Kong, Peoples R China 9.Hong Kong Authenticat Ctr Valuable Chinese Med, Hong Kong, Peoples R China
推荐引用方式 GB/T 7714	Li,Li-Feng,But,Grace Wing-Chiu,Zhang,Quan-Wei,et al. A specific and bioactive polysaccharide marker for Cordyceps[J]. CARBOHYDRATE POLYMERS,2021,269:118343.
APA	Li,Li-Feng.,But,Grace Wing-Chiu.,Zhang,Quan-Wei.,Liu,Man.,Chen,Miao-Miao.,...&Sun,Han-Dong.(2021).A specific and bioactive polysaccharide marker for Cordyceps.CARBOHYDRATE POLYMERS,269,118343.
MLA	Li,Li-Feng,et al."A specific and bioactive polysaccharide marker for Cordyceps".CARBOHYDRATE POLYMERS 269(2021):118343.

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