Illilanceolide A, a unique seco-prezizaane sesquiterpenoid with 5/5/6 tricyclic scaffold from the fruits of Illicium lanceolatum A. C. Smith

doi:10.1016/j.tetlet.2021.153022

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	Illilanceolide A, a unique seco-prezizaane sesquiterpenoid with 5/5/6 tricyclic scaffold from the fruits of Illicium lanceolatum A. C. Smith
	Nie,Wei ; Ding,Lin-Fen ; Lei,Tie ; Pan,Zheng-Hong ; Song,Liu-Dong ; Wu,Xing-De ; Zhao,Qin-Shi
	2021
发表期刊	TETRAHEDRON LETTERS
ISSN	0040-4039
卷号	70 页码:153022
摘要	A unique seco-prezizaane sesquiterpenoid with 5/5/6 tricyclic skeleton, illilanceolide A (1), and two rare 10,14-cycloseco-prezizaane sesquiterpenoids, 2-oxo-6-dehydroxyneoanisatinic acid (2) and 3,4-anhydro-2-oxo-6-dehydroxyneoanisatinic acid (3), together with two known sesquiterpenoids, were isolated from the fruits of Illicium lanceolatum. Their structures and absolute configurations were elucidated on the basis of extensive H-1, C-13, and 2D NMR, and HRESIMS data, as well as single-crystal X-ray diffraction analysis. Compounds 2-4 enhanced the neurite outgrowth of NGF-mediated PC12 cells at a concentration of 10 mu M with differentiation rates of 13.33%, 10.90%, and 11.76%, respectively. Moreover, compounds 2-4 were found to exhibit moderate neuroprotective effect against MPP+-induced PC12 cell damage. (C) 2021 Elsevier Ltd. All rights reserved.
关键词	Illicium lanceolatum A. C. Smith Seco-prezizaane sesquiterpenoid Neurotrophic activity Neuroprotective effect NEUROTROPHIC ACTIVITY PERICARPS ANISATIN
DOI	10.1016/j.tetlet.2021.153022
WOS记录号	WOS:000641047500024
引用统计
文献类型	期刊论文
条目标识符	http://ir.kib.ac.cn/handle/151853/73204
专题	中国科学院昆明植物研究所
作者单位	1.[Nie, Wei 2.Ding, Lin-Fen 3.Lei, Tie 4.Wu, Xing-De 5.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Yunnan, Peoples R China 6.Kunming Med Univ, Sch Pharmaceut Sci, Kunming 650500, Yunnan, Peoples R China 7.Kunming Med Univ, Yunnan Key Lab Pharmacol Nat Prod, Kunming 650500, Yunnan, Peoples R China 8.Chinese Acad Sci, Guangxi Inst Bot, Guangxi Key Lab Funct Phytochem Res & Utilizat, Guilin 541006, Peoples R China
推荐引用方式 GB/T 7714	Nie,Wei,Ding,Lin-Fen,Lei,Tie,et al. Illilanceolide A, a unique seco-prezizaane sesquiterpenoid with 5/5/6 tricyclic scaffold from the fruits of Illicium lanceolatum A. C. Smith[J]. TETRAHEDRON LETTERS,2021,70:153022.
APA	Nie,Wei.,Ding,Lin-Fen.,Lei,Tie.,Pan,Zheng-Hong.,Song,Liu-Dong.,...&Zhao,Qin-Shi.(2021).Illilanceolide A, a unique seco-prezizaane sesquiterpenoid with 5/5/6 tricyclic scaffold from the fruits of Illicium lanceolatum A. C. Smith.TETRAHEDRON LETTERS,70,153022.
MLA	Nie,Wei,et al."Illilanceolide A, a unique seco-prezizaane sesquiterpenoid with 5/5/6 tricyclic scaffold from the fruits of Illicium lanceolatum A. C. Smith".TETRAHEDRON LETTERS 70(2021):153022.

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