Anti-Food Allergic Alkaloids from the Lotus Seed Pot

doi:10.1002/cbdv.202100770

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	Anti-Food Allergic Alkaloids from the Lotus Seed Pot
	Cao,Tuan-Wu ; Xie,Chun-Lan ; Chen,Chao-Qun ; He,Zhi-Hui ; Yan,Qing-Xiang ; Xu,Gang; Yang,Xian-Wen
	2021
发表期刊	CHEMISTRY & BIODIVERSITY
ISSN	1612-1872
卷号	18 期号:12 页码:e2100770
摘要	Lotus seed pod (LSP) has been used as traditional herbal cuisine to modulate immunity. From the AcOEt-soluble extract of LSP, one new aporphine alkaloid, N-[2-(2H-phenanthro[3,4-d][1,3]dioxol-5-yl)ethyl]acetamide (nelunucine A, 1) was obtained along with 19 known ones. Their structures were established by detailed analysis of the 1D-, 2D-NMR, and HR-ESI-MS data. N-Nornuciferine (9) and lirinidine (10) showed potent in vitro anti-food allergic activity with IC50 values of 40.0 and 55.4 mu M, respectively, compared to 91.4 mu M for loratadine, the positive control.
关键词	Nelumbo nucifera lotus seed pod alkaloids anti-food allergy APORPHINE ALKALOIDS NELUMBO-NUCIFERA ANTIOXIDANT LEAVES
DOI	10.1002/cbdv.202100770
WOS记录号	WOS:000716555700001
引用统计
文献类型	期刊论文
条目标识符	http://ir.kib.ac.cn/handle/151853/73144
专题	中国科学院昆明植物研究所
作者单位	1.Yangtze Normal Univ, Lab Nat Med Res & Dev Wuling Mt, Sch Chem & Chem Engn, Fuling 408100, Peoples R China 2.[Xie, Chun-Lan 3.He, Zhi-Hui 4.Yan, Qing-Xiang 5.Minist Nat Resources, Inst Oceanog 3, Key Lab Marine Biogenet Resources, 184 Daxue Rd, Xiamen 361005, Peoples R China 6.[Chen, Chao-Qun 7.Chinese Acad Sci, State Key Lab Phytochem & Plant Resources West Ch, Kunming Inst Bot, Kunming 650201, Yunnan, Peoples R China 8.Chinese Acad Sci, Yunnan Key Lab Nat Med Chem, Kunming Inst Bot, Kunming 650201, Yunnan, Peoples R China
推荐引用方式 GB/T 7714	Cao,Tuan-Wu,Xie,Chun-Lan,Chen,Chao-Qun,et al. Anti-Food Allergic Alkaloids from the Lotus Seed Pot[J]. CHEMISTRY & BIODIVERSITY,2021,18(12):e2100770.
APA	Cao,Tuan-Wu.,Xie,Chun-Lan.,Chen,Chao-Qun.,He,Zhi-Hui.,Yan,Qing-Xiang.,...&Yang,Xian-Wen.(2021).Anti-Food Allergic Alkaloids from the Lotus Seed Pot.CHEMISTRY & BIODIVERSITY,18(12),e2100770.
MLA	Cao,Tuan-Wu,et al."Anti-Food Allergic Alkaloids from the Lotus Seed Pot".CHEMISTRY & BIODIVERSITY 18.12(2021):e2100770.

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