Resorcinol derivatives with alpha-glucosidase inhibitory activities from Syzygium samarangense

doi:10.1080/14786419.2020.1805606

KIB OpenIR

	Resorcinol derivatives with alpha-glucosidase inhibitory activities from Syzygium samarangense
	Hu,Yi-Kao ; Wang,Li; Wang,Ji-Hua ; Li,Meng-Jia ; Li,Feng ; Yang,Jing; Zhao,Yong
	2021
发表期刊	NATURAL PRODUCT RESEARCH
ISSN	1478-6419
卷号	35 期号:24 页码:5948-5953
摘要	Nine resorcinol derivatives including two new ones, 5-[(8Z,11Z,14Z)-nonadeca-8,11,14-trienyl] resorcinol (1) and 5-[(8Z,11Z,14E)-heptadeca-8,11,14-trienyl] resorcinol (2), were isolated from the leaves ofSyzygium samarangense. The new structures were elucidated by means of extensive spectroscopic techniques including interpretation of 1D and 2D NMR spectra. Among them, compounds3,4,6 and 7 exhibited significant alpha-glucosidase inhibitory activities with IC50 of 3.16, 3.16, 2.34 and 0.99 mu M, respectively. This finding provides evidence that resorcinol derivatives with long aliphatic chain function as new promising antidiabetic alternatives.[GRAPHICS].
关键词	Syzygium samarangense resorcinol derivatives alpha-glucosidase inhibitory activity TRITERPENOIDS LEAVES
DOI	10.1080/14786419.2020.1805606
WOS记录号	WOS:000558965200001
引用统计	被引频次：5[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.kib.ac.cn/handle/151853/73010
专题	中国科学院昆明植物研究所
作者单位	1.Yunnan Normal Univ, Coll Chem & Chem Engn, Kunming, Yunnan, Peoples R China 2.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming, Yunnan, Peoples R China
推荐引用方式 GB/T 7714	Hu,Yi-Kao,Wang,Li,Wang,Ji-Hua,et al. Resorcinol derivatives with alpha-glucosidase inhibitory activities from Syzygium samarangense[J]. NATURAL PRODUCT RESEARCH,2021,35(24):5948-5953.
APA	Hu,Yi-Kao.,Wang,Li.,Wang,Ji-Hua.,Li,Meng-Jia.,Li,Feng.,...&Zhao,Yong.(2021).Resorcinol derivatives with alpha-glucosidase inhibitory activities from Syzygium samarangense.NATURAL PRODUCT RESEARCH,35(24),5948-5953.
MLA	Hu,Yi-Kao,et al."Resorcinol derivatives with alpha-glucosidase inhibitory activities from Syzygium samarangense".NATURAL PRODUCT RESEARCH 35.24(2021):5948-5953.