| Chemical Investigation of the Secondary Metabolites of Streptomyces sp. 4205 | |
Gu, Cheng-Zhen1; Lv, Jing1; Yuan, Sheng-Hao1; Song, Yuan-Yuan2; Yang, Chong-Ren3; Zhang, Ying-Jun3 ; Zeng, Ren-Sen2
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| Corresponding Author | Zhang, Ying-Jun(zhangyj@mail.kib.ac.cn) ; Zeng, Ren-Sen(rszeng@scau.edu.cn) |
| 2019-06-01 | |
| Source Publication | NATURAL PRODUCT COMMUNICATIONS
 |
| ISSN | 1934-578X |
| Volume | 14Issue:6Pages:3 |
| Abstract | Chemical investigation of the secondary metabolites of Streptomyces sp. 4205 resulted in the isolation of 1 new compound, named as 3,8-dimethyl-9-hydroxy-cyclodeca-3,5-diene-1,2-diketone (1), along with 3 known compounds. Their structures were elucidated on the basis of extensive spectroscopic analysis. All the compounds were tested for their inhibitory activity against Candida albicans ATCC 90028, Escherichia coli ATCC 35218, Pseudomonas aeruginosa ATCC 28753, Crytococcus neoformans ATCC 90113, Mycobacterium intracellulare ATCC 23068, Aspergillus fumigatus ATCC 90906, and methicillin-resistant Staphylococcus aureus ATCC 43300. Compound 1 showed activity against C. albicans ATCC 90028, with minimum inhibitory concentration and half-maximal inhibitory concentration values of 10.0 and 1.0 mg/mL, respectively. |
| Keyword | Streptomyces sp 4205 chemical components antibiotic |
| DOI | 10.1177/1934578X19859130 |
| Indexed By | SCI |
| Language | 英语 |
| WOS Research Area | Pharmacology & Pharmacy ; Food Science & Technology |
| WOS Subject | Chemistry, Medicinal ; Food Science & Technology |
| WOS ID | WOS:000475765700074 |
| Citation statistics | |
| Document Type | 期刊论文 |
| Identifier | http://ir.kib.ac.cn/handle/151853/68148 |
| Collection | 植物化学与西部植物资源持续利用国家重点实验室 |
| Corresponding Author | Zhang, Ying-Jun; Zeng, Ren-Sen |
| Affiliation | 1.Fujian Agr & Forestry Univ, Coll Life Sci, Fuzhou, Fujian, Peoples R China 2.Fujian Agr & Forestry Univ, Coll Crop Sci, Fuzhou 350002, Fujian, Peoples R China 3.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Yunnan, Peoples R China |
| Recommended Citation GB/T 7714 | Gu, Cheng-Zhen,Lv, Jing,Yuan, Sheng-Hao,et al. Chemical Investigation of the Secondary Metabolites of Streptomyces sp. 4205[J]. NATURAL PRODUCT COMMUNICATIONS,2019,14(6):3. |
| APA | Gu, Cheng-Zhen.,Lv, Jing.,Yuan, Sheng-Hao.,Song, Yuan-Yuan.,Yang, Chong-Ren.,...&Zeng, Ren-Sen.(2019).Chemical Investigation of the Secondary Metabolites of Streptomyces sp. 4205.NATURAL PRODUCT COMMUNICATIONS,14(6),3. |
| MLA | Gu, Cheng-Zhen,et al."Chemical Investigation of the Secondary Metabolites of Streptomyces sp. 4205".NATURAL PRODUCT COMMUNICATIONS 14.6(2019):3. |
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