Alkaloids from the roots of Stemona tuberosa and their anti-tobacco mosaic virus activities

doi:10.1016/j.tet.2018.11.064

	Alkaloids from the roots of Stemona tuberosa and their anti-tobacco mosaic virus activities
	Hu, Zhan-Xing1,2,3,4,5,6 ; Tang, Hong-Yu 1,7; Guo, Jie 1; Aisa, Haji Aker 2; Zhang, Yu1 ; Hao, Xiao-Jiang1,4,5,6
通讯作者	Zhang, Yu(zhangyu@mail.kib.ac.cn) ; Hao, Xiao-Jiang(haoxj@mail.kib.ac.cn)
	2019-03-22
发表期刊	TETRAHEDRON
ISSN	0040-4020
卷号	75 期号:12 页码:1711-1716
摘要	Stemtuberlines A (1) and B (2), two new alkaloids with a unique tricyclic pyrrolo [3,2,1-jk]benzazepine-12-one nucleus, three new croomine-type alkaloids, stemtuberlines C-E (3-5), together with seven known ones were isolated from the roots of Stemona tuberosa. The structures of the new alkaloids were elucidated based on a comprehensive spectroscopic data analysis. The absolute configurations of 1 and 2 were determined by quantum ECD calculations. The anti-tobacco mosaic virus activity of the Stemona alkaloids was firstly evaluated and compound 11 exhibited significant anti-tobacco mosaic virus activity with the curative inhibition rate of 84.6% at concentration of 50 mu g/mL. (C) 2018 Elsevier Ltd. All rights reserved.
关键词	Stemona tuberosa Stemona alkaloids Stemtuberline A Anti-TMV
DOI	10.1016/j.tet.2018.11.064
收录类别	SCI
语种	英语
WOS记录号	WOS:000462418900021
引用统计
文献类型	期刊论文
条目标识符	http://ir.kib.ac.cn/handle/151853/67671
专题	植物化学与西部植物资源持续利用国家重点实验室
通讯作者	Zhang, Yu; Hao, Xiao-Jiang
作者单位	1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Yunnan, Peoples R China 2.Chinese Acad Sci, Xinjiang Tech Inst Phys & Chem, Urumqi 830011, Peoples R China 3.Univ Chinese Acad Sci, Yuquan Rd 19, Beijing 100049, Peoples R China 4.Guizhou Med Univ, State Key Lab Funct & Applicat Med Plants, Guiyang 550014, Guizhou, Peoples R China 5.Key Lab Chem Nat Prod Guizhou Prov, Guiyang 550002, Guizhou, Peoples R China 6.Chinese Acad Sci, Guiyang 550002, Guizhou, Peoples R China 7.Yunnan Univ, Sch Chem Sci & Technol, Kunming 650091, Yunnan, Peoples R China
推荐引用方式 GB/T 7714	Hu, Zhan-Xing,Tang, Hong-Yu,Guo, Jie,et al. Alkaloids from the roots of Stemona tuberosa and their anti-tobacco mosaic virus activities[J]. TETRAHEDRON,2019,75(12):1711-1716.
APA	Hu, Zhan-Xing,Tang, Hong-Yu,Guo, Jie,Aisa, Haji Aker,Zhang, Yu,&Hao, Xiao-Jiang.(2019).Alkaloids from the roots of Stemona tuberosa and their anti-tobacco mosaic virus activities.TETRAHEDRON,75(12),1711-1716.
MLA	Hu, Zhan-Xing,et al."Alkaloids from the roots of Stemona tuberosa and their anti-tobacco mosaic virus activities".TETRAHEDRON 75.12(2019):1711-1716.

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