Alkaloids from the roots of Stemona tuberosa and their anti-tobacco mosaic virus activities
Hu, Zhan-Xing1,2,3,4,5,6; Tang, Hong-Yu1,7; Guo, Jie1; Aisa, Haji Aker2; Zhang, Yu1; Hao, Xiao-Jiang1,4,5,6
Corresponding AuthorZhang, Yu(zhangyu@mail.kib.ac.cn) ; Hao, Xiao-Jiang(haoxj@mail.kib.ac.cn)
2019-03-22
Source PublicationTETRAHEDRON
ISSN0040-4020
Volume75Issue:12Pages:1711-1716
AbstractStemtuberlines A (1) and B (2), two new alkaloids with a unique tricyclic pyrrolo [3,2,1-jk]benzazepine-12-one nucleus, three new croomine-type alkaloids, stemtuberlines C-E (3-5), together with seven known ones were isolated from the roots of Stemona tuberosa. The structures of the new alkaloids were elucidated based on a comprehensive spectroscopic data analysis. The absolute configurations of 1 and 2 were determined by quantum ECD calculations. The anti-tobacco mosaic virus activity of the Stemona alkaloids was firstly evaluated and compound 11 exhibited significant anti-tobacco mosaic virus activity with the curative inhibition rate of 84.6% at concentration of 50 mu g/mL. (C) 2018 Elsevier Ltd. All rights reserved.
KeywordStemona tuberosa Stemona alkaloids Stemtuberline A Anti-TMV
DOI10.1016/j.tet.2018.11.064
Indexed BySCI
Language英语
WOS Research AreaChemistry
WOS SubjectChemistry, Organic
WOS IDWOS:000462418900021
Citation statistics
Cited Times:1[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://ir.kib.ac.cn/handle/151853/67671
Collection植物化学与西部植物资源持续利用国家重点实验室
Corresponding AuthorZhang, Yu; Hao, Xiao-Jiang
Affiliation1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Yunnan, Peoples R China
2.Chinese Acad Sci, Xinjiang Tech Inst Phys & Chem, Urumqi 830011, Peoples R China
3.Univ Chinese Acad Sci, Yuquan Rd 19, Beijing 100049, Peoples R China
4.Guizhou Med Univ, State Key Lab Funct & Applicat Med Plants, Guiyang 550014, Guizhou, Peoples R China
5.Key Lab Chem Nat Prod Guizhou Prov, Guiyang 550002, Guizhou, Peoples R China
6.Chinese Acad Sci, Guiyang 550002, Guizhou, Peoples R China
7.Yunnan Univ, Sch Chem Sci & Technol, Kunming 650091, Yunnan, Peoples R China
Recommended Citation
GB/T 7714
Hu, Zhan-Xing,Tang, Hong-Yu,Guo, Jie,et al. Alkaloids from the roots of Stemona tuberosa and their anti-tobacco mosaic virus activities[J]. TETRAHEDRON,2019,75(12):1711-1716.
APA Hu, Zhan-Xing,Tang, Hong-Yu,Guo, Jie,Aisa, Haji Aker,Zhang, Yu,&Hao, Xiao-Jiang.(2019).Alkaloids from the roots of Stemona tuberosa and their anti-tobacco mosaic virus activities.TETRAHEDRON,75(12),1711-1716.
MLA Hu, Zhan-Xing,et al."Alkaloids from the roots of Stemona tuberosa and their anti-tobacco mosaic virus activities".TETRAHEDRON 75.12(2019):1711-1716.
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