| NCP activates chloroplast transcription by controlling phytochrome-dependent dual nuclear and plastidial switches | |
| Yang, Emily J.1,2,6; Yoo, Chan Yul1; Liu, Jiangxin3,4; Wang, He1; Cao, Jun5; Li, Fay-Wei2,7; Pryer, Kathleen M.2; Sun, Tai-ping2; Weigel, Detlef5; Zhou, Pei3; Chen, Meng1 | |
| Corresponding Author | Zhou, Pei(peizhou@biochem.duke.edu) ; Chen, Meng(meng.chen@ucr.edu) |
| 2019-06-14 | |
| Source Publication | NATURE COMMUNICATIONS
 |
| ISSN | 2041-1723 |
| Volume | 10Pages:13 |
| Abstract | Phytochromes initiate chloroplast biogenesis by activating genes encoding the photosynthetic apparatus, including photosynthesis-associated plastid-encoded genes (PhAPGs). PhAPGs are transcribed by a bacterial-type RNA polymerase (PEP), but how phytochromes in the nucleus activate chloroplast gene expression remains enigmatic. We report here a forward genetic screen in Arabidopsis that identified NUCLEAR CONTROL OF PEP ACTIVITY (NCP) as a necessary component of phytochrome signaling for PhAPG activation. NCP is dual-targeted to plastids and the nucleus. While nuclear NCP mediates the degradation of two repressors of chloroplast biogenesis, PIF1 and PIF3, NCP in plastids promotes the assembly of the PEP complex for PhAPG transcription. NCP and its paralog RCB are non-catalytic thioredoxin-like proteins that diverged in seed plants to adopt nonredundant functions in phytochrome signaling. These results support a model in which phytochromes control PhAPG expression through light-dependent double nuclear and plastidial switches that are linked by evolutionarily conserved and dual-localized regulatory proteins. |
| DOI | 10.1038/s41467-019-10517-1 |
| Indexed By | SCI |
| Language | 英语 |
| WOS ID | WOS:000471586700007 |
| Citation statistics | |
| Document Type | 期刊论文 |
| Identifier | http://ir.kib.ac.cn/handle/151853/67256 |
| Collection | 植物化学与西部植物资源持续利用国家重点实验室 |
| Corresponding Author | Zhou, Pei; Chen, Meng |
| Affiliation | 1.Univ Calif Riverside, Dept Bot & Plant Sci, Inst Integrat Genome Biol, Riverside, CA 92521 USA 2.Duke Univ, Dept Biol, Durham, NC 27708 USA 3.Duke Univ, Med Ctr, Dept Biochem, Durham, NC 27710 USA 4.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Yunnan, Peoples R China 5.Max Planck Inst Dev Biol, Dept Mol Biol, D-72076 Tubingen, Germany 6.Columbia Univ, Dept Pathol & Cell Biol, Med Ctr, New York, NY 10032 USA 7.Boyce Thompson Inst Plant Res, Ithaca, NY 14853 USA |
| Recommended Citation GB/T 7714 | Yang, Emily J.,Yoo, Chan Yul,Liu, Jiangxin,et al. NCP activates chloroplast transcription by controlling phytochrome-dependent dual nuclear and plastidial switches[J]. NATURE COMMUNICATIONS,2019,10:13. |
| APA | Yang, Emily J..,Yoo, Chan Yul.,Liu, Jiangxin.,Wang, He.,Cao, Jun.,...&Chen, Meng.(2019).NCP activates chloroplast transcription by controlling phytochrome-dependent dual nuclear and plastidial switches.NATURE COMMUNICATIONS,10,13. |
| MLA | Yang, Emily J.,et al."NCP activates chloroplast transcription by controlling phytochrome-dependent dual nuclear and plastidial switches".NATURE COMMUNICATIONS 10(2019):13. |
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| Yang-2019-NCP activa（2676KB） | 期刊论文 | 出版稿 | 开放获取 | CC BY-NC-SA | View Download | |
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