Irpexolidal Represents a Class of Triterpenoid from the Fruiting Bodies of the Medicinal Fungus Irpex lacteus
Tang, Yang1,2; Zhao, Zhen-Zhu3; Hu, Kun2; Feng, Tao1; Li, Zheng-Hui1; Chen, He-Ping1,2; Liu, Ji-Kai1,2
2019-02-15
Source PublicationJOURNAL OF ORGANIC CHEMISTRY
ISSN0022-3263
Volume84Issue:4Pages:1845-1852
AbstractIrpexolidal (1), a triterpenoid with an unprecedented carbon skeleton, along with its biogenetic-related compound irpexolide A (2), were isolated from the fruiting bodies of the medicinal fungus Irpex lacteus. Irpexolidal features a 6/ 5/6/5/6/5-fused polycyclic skeletal system which arises from the eburicane-type triterpene by a 6,7-seco-6,8-cyclo pattern. The structures of 1 and 2 were established by means of extensive spectroscopic techniques, ECD calculation, and DP4+ probability based on GIAO NMR chemical shift calculations. The plausible biosynthetic pathways for compounds 1 and 2 were proposed. Their biological activities were evaluated.
Indexed BySCI
Language英语
Document Type期刊论文
Identifierhttp://ir.kib.ac.cn/handle/151853/65128
Collection植物化学与西部植物资源持续利用国家重点实验室
Corresponding AuthorChen, He-Ping; Liu, Ji-Kai
Affiliation1.South Cent Univ Nationalities, Sch Pharmaceut Sci, Wuhan 430074, Hubei, Peoples R China
2.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Yunnan, Peoples R China
3.Henan Univ Chinese Med, Coll Pharm, Zhengzhou 450008, Henan, Peoples R China
Recommended Citation
GB/T 7714
Tang, Yang,Zhao, Zhen-Zhu,Hu, Kun,et al. Irpexolidal Represents a Class of Triterpenoid from the Fruiting Bodies of the Medicinal Fungus Irpex lacteus[J]. JOURNAL OF ORGANIC CHEMISTRY,2019,84(4):1845-1852.
APA Tang, Yang.,Zhao, Zhen-Zhu.,Hu, Kun.,Feng, Tao.,Li, Zheng-Hui.,...&Liu, Ji-Kai.(2019).Irpexolidal Represents a Class of Triterpenoid from the Fruiting Bodies of the Medicinal Fungus Irpex lacteus.JOURNAL OF ORGANIC CHEMISTRY,84(4),1845-1852.
MLA Tang, Yang,et al."Irpexolidal Represents a Class of Triterpenoid from the Fruiting Bodies of the Medicinal Fungus Irpex lacteus".JOURNAL OF ORGANIC CHEMISTRY 84.4(2019):1845-1852.
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