| Garsubelone A, the First Dimeric Polycyclic Polyprenylated Acylphloroglucinols with Complicated Heptacyclic Architecture from Garcinia subelliptica | |
Wang, Yong-Ling1,2; Ye, Yan-Song3,4,5 ; Fu, Wen-Wei1,2; Wu, Rong1,2; Xiang, Qian1,2; Lao, Yuan-Zhi1,2; Yang, Jin-Ling1,2; Tan, Hong-Sheng1,2; Yang, Xing-Wei3,4; Yang, Bai-Can1,2; Xu, Hong-Xi1,2; Xu, Gang3,4
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| Corresponding Author | Xu, Hong-Xi(xugang008@mail.kib.ac.cn) ; Xu, Gang(xuhongxi88@gmail.com) |
| 2019-03-01 | |
| Source Publication | ORGANIC LETTERS
 |
| ISSN | 1523-7060 |
| Volume | 21Issue:5Pages:1534-1537 |
| Abstract | Garsubelone A (1), the first dimeric polycyclic polyprenylated acylphloroglucinols type metabolite featuring a complicated 6/6/6/6/6/6/6 heptacyclic architecture containing 10 stereogenic centers, was isolated from Garcinia subelliptica. Biogenetically, this compound was constructed by the plausible monomeric precursor, garsubelone B (2) and secohyperforin, via a key Diels-Alder cycloaddition to form an unique 2-oxabicyclo[3.3.1]nonane core. Their structures and absolute configurations were determined by comprehensive spectroscopic and X-ray diffraction techniques. The cytotoxic activities of these isolates were also evaluated. |
| DOI | 10.1021/acs.orglett.9b00388 |
| Indexed By | SCI |
| Language | 英语 |
| WOS ID | WOS:000460491700063 |
| Citation statistics | |
| Document Type | 期刊论文 |
| Identifier | http://ir.kib.ac.cn/handle/151853/64994 |
| Collection | 植物化学与西部植物资源持续利用国家重点实验室 |
| Corresponding Author | Xu, Hong-Xi; Xu, Gang |
| Affiliation | 1.Shanghai Univ Tradit Chinese Med, Sch Pharm, Shanghai 201203, Peoples R China 2.Shanghai Coll TCM New Drug Discovery, Engn Res Ctr, Shanghai 201203, Peoples R China 3.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Yunnan, Peoples R China 4.Yunnan Key Lab Nat Med Chem, Kunming 650201, Yunnan, Peoples R China 5.Univ Chinese Acad Sci, Beijing 100049, Peoples R China |
| Recommended Citation GB/T 7714 | Wang, Yong-Ling,Ye, Yan-Song,Fu, Wen-Wei,et al. Garsubelone A, the First Dimeric Polycyclic Polyprenylated Acylphloroglucinols with Complicated Heptacyclic Architecture from Garcinia subelliptica[J]. ORGANIC LETTERS,2019,21(5):1534-1537. |
| APA | Wang, Yong-Ling.,Ye, Yan-Song.,Fu, Wen-Wei.,Wu, Rong.,Xiang, Qian.,...&Xu, Gang.(2019).Garsubelone A, the First Dimeric Polycyclic Polyprenylated Acylphloroglucinols with Complicated Heptacyclic Architecture from Garcinia subelliptica.ORGANIC LETTERS,21(5),1534-1537. |
| MLA | Wang, Yong-Ling,et al."Garsubelone A, the First Dimeric Polycyclic Polyprenylated Acylphloroglucinols with Complicated Heptacyclic Architecture from Garcinia subelliptica".ORGANIC LETTERS 21.5(2019):1534-1537. |
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| File Name/Size | DocType | Version | Access | License | ||
| Wang-2019-Garsubelon（777KB） | 期刊论文 | 出版稿 | 开放获取 | CC BY-NC-SA | View Application Full Text | |
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