Garsubelone A, the First Dimeric Polycyclic Polyprenylated Acylphloroglucinols with Complicated Heptacyclic Architecture from Garcinia subelliptica

doi:10.1021/acs.orglett.9b00388

	Garsubelone A, the First Dimeric Polycyclic Polyprenylated Acylphloroglucinols with Complicated Heptacyclic Architecture from Garcinia subelliptica
	Wang, Yong-Ling 1,2; Ye, Yan-Song3,4,5 ; Fu, Wen-Wei 1,2; Wu, Rong 1,2; Xiang, Qian 1,2; Lao, Yuan-Zhi 1,2; Yang, Jin-Ling 1,2; Tan, Hong-Sheng 1,2; Yang, Xing-Wei3,4 ; Yang, Bai-Can 1,2; Xu, Hong-Xi 1,2; Xu, Gang3,4
通讯作者	Xu, Hong-Xi(xugang008@mail.kib.ac.cn) ; Xu, Gang(xuhongxi88@gmail.com)
	2019-03-01
发表期刊	ORGANIC LETTERS
ISSN	1523-7060
卷号	21 期号:5 页码:1534-1537
摘要	Garsubelone A (1), the first dimeric polycyclic polyprenylated acylphloroglucinols type metabolite featuring a complicated 6/6/6/6/6/6/6 heptacyclic architecture containing 10 stereogenic centers, was isolated from Garcinia subelliptica. Biogenetically, this compound was constructed by the plausible monomeric precursor, garsubelone B (2) and secohyperforin, via a key Diels-Alder cycloaddition to form an unique 2-oxabicyclo[3.3.1]nonane core. Their structures and absolute configurations were determined by comprehensive spectroscopic and X-ray diffraction techniques. The cytotoxic activities of these isolates were also evaluated.
DOI	10.1021/acs.orglett.9b00388
收录类别	SCI
语种	英语
WOS记录号	WOS:000460491700063
引用统计
文献类型	期刊论文
条目标识符	http://ir.kib.ac.cn/handle/151853/64994
专题	植物化学与西部植物资源持续利用国家重点实验室
通讯作者	Xu, Hong-Xi; Xu, Gang
作者单位	1.Shanghai Univ Tradit Chinese Med, Sch Pharm, Shanghai 201203, Peoples R China 2.Shanghai Coll TCM New Drug Discovery, Engn Res Ctr, Shanghai 201203, Peoples R China 3.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Yunnan, Peoples R China 4.Yunnan Key Lab Nat Med Chem, Kunming 650201, Yunnan, Peoples R China 5.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
推荐引用方式 GB/T 7714	Wang, Yong-Ling,Ye, Yan-Song,Fu, Wen-Wei,et al. Garsubelone A, the First Dimeric Polycyclic Polyprenylated Acylphloroglucinols with Complicated Heptacyclic Architecture from Garcinia subelliptica[J]. ORGANIC LETTERS,2019,21(5):1534-1537.
APA	Wang, Yong-Ling.,Ye, Yan-Song.,Fu, Wen-Wei.,Wu, Rong.,Xiang, Qian.,...&Xu, Gang.(2019).Garsubelone A, the First Dimeric Polycyclic Polyprenylated Acylphloroglucinols with Complicated Heptacyclic Architecture from Garcinia subelliptica.ORGANIC LETTERS,21(5),1534-1537.
MLA	Wang, Yong-Ling,et al."Garsubelone A, the First Dimeric Polycyclic Polyprenylated Acylphloroglucinols with Complicated Heptacyclic Architecture from Garcinia subelliptica".ORGANIC LETTERS 21.5(2019):1534-1537.

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