Comparative study on "long-dan", "qin-jiao" and their adulterants by HPLC analysis.

	Comparative study on "long-dan", "qin-jiao" and their adulterants by HPLC analysis.
	Liu, Fang-Fang; Wang, Yan-Ming; Zhu, Hong-Tao; Wang, Dong; Yang, Chong-Ren; Xu, Min; Zhang, Ying-Jun
	2014
发表期刊	Natural products and bioprospecting
ISSN	2192-2195
卷号	4 期号:5 页码:297-308
摘要	Long-Dan and "Qin-Jiao" are two important TCM herbs since ancient times in China. In the Chinese Pharmacopoeia, the dried roots and rhizomes of four species from the genus Gentiana, e.g. Gentiana manshurica, G. scabra, G. triflora and G. rigescens, are recorded under the name of Gentianae Radix et Rhizoma ("Long-Dan" in Chinese), while the other four species from the same genus including G. macrophylla, G. crassicaulis, G. straminea and G. duhurica are recorded and used as the raw materials of Gentianae Macrophyllae Radix ("Qin-Jiao" in Chinese). On the basis of the establishment of a validated HPLC-UV method for quantifying simultaneously, five iridoid glycosides, e.g. loganic acid (1), swertiamarinin (2), gentiopicroside (3), sweroside (4) and 2'-(o,m-dihydroxybenzyl)sweroside (5) have been used successfully as chemical markers for the comparison of the species used as "Long-Dan", "Qin-Jiao" and their adulterants in the present study. The results suggested that four iridoid glycosides 1-4 commonly existed in both "Long-Dan" and "Qin-Jiao", while 2'-(o,m-dihydroxybenzyl)sweroside (5) also existed as one of the major components in "Dian-Long-Dan" species. Moreover, the contents of compounds 1-5 were various in different "Long-Dan" and "Qin-Jiao" species. Herein, we profiled and compared three "Long-Dan" species, four "Qin-Jiao" species and five adulterants by applying multivariate statistical techniques to their HPLC data sets to establish the differences and/or similarities.
文献类型	期刊论文
条目标识符	http://ir.kib.ac.cn/handle/151853/64910
专题	植物化学与西部植物资源持续利用国家重点实验室
推荐引用方式 GB/T 7714	Liu, Fang-Fang,Wang, Yan-Ming,Zhu, Hong-Tao,et al. Comparative study on "long-dan", "qin-jiao" and their adulterants by HPLC analysis.[J]. Natural products and bioprospecting,2014,4(5):297-308.
APA	Liu, Fang-Fang.,Wang, Yan-Ming.,Zhu, Hong-Tao.,Wang, Dong.,Yang, Chong-Ren.,...&Zhang, Ying-Jun.(2014).Comparative study on "long-dan", "qin-jiao" and their adulterants by HPLC analysis..Natural products and bioprospecting,4(5),297-308.
MLA	Liu, Fang-Fang,et al."Comparative study on "long-dan", "qin-jiao" and their adulterants by HPLC analysis.".Natural products and bioprospecting 4.5(2014):297-308.