Cycloartane Glycosides from the Roots of Cimicifuga foetida with Wnt Signaling Pathway Inhibitory Activity.

	Cycloartane Glycosides from the Roots of Cimicifuga foetida with Wnt Signaling Pathway Inhibitory Activity.
	Zhu, Di-Fan; Zhu, Guo-Lei; Kong, Ling-Mei; Bao, Ni-Man; Zhou, Lin; Nian, Yin; Qiu, Ming-Hua
	2015
发表期刊	Natural products and bioprospecting
ISSN	2192-2195
卷号	5 期号:2 页码:61-67
摘要	Four new 9,19-cycloartane triterpenoids, cimilactone E (1), cimilactone F (2), 2'-O-(E)-butenoyl-23-epi-26-deoxyactein (3), and 2',12beta-O-diacetylcimiracemonol-3-O-beta-d-xylopyranoside (4), together with four known constituents (5-8) were isolated from the roots of Cimicifuga foetida. The new structures were elucidated by extensive spectroscopic analysis. In addition, compounds 7 and 8 showed significant Wnt signaling pathway inhibitory activity, with IC50 values of 3.33 and 13.34muM, respectively, using the luciferase reporter gene assay.
文献类型	期刊论文
条目标识符	http://ir.kib.ac.cn/handle/151853/64903
专题	植物化学与西部植物资源持续利用国家重点实验室
推荐引用方式 GB/T 7714	Zhu, Di-Fan,Zhu, Guo-Lei,Kong, Ling-Mei,et al. Cycloartane Glycosides from the Roots of Cimicifuga foetida with Wnt Signaling Pathway Inhibitory Activity.[J]. Natural products and bioprospecting,2015,5(2):61-67.
APA	Zhu, Di-Fan.,Zhu, Guo-Lei.,Kong, Ling-Mei.,Bao, Ni-Man.,Zhou, Lin.,...&Qiu, Ming-Hua.(2015).Cycloartane Glycosides from the Roots of Cimicifuga foetida with Wnt Signaling Pathway Inhibitory Activity..Natural products and bioprospecting,5(2),61-67.
MLA	Zhu, Di-Fan,et al."Cycloartane Glycosides from the Roots of Cimicifuga foetida with Wnt Signaling Pathway Inhibitory Activity.".Natural products and bioprospecting 5.2(2015):61-67.