Gamma-aminobutyric acid mediates nicotine biosynthesis in tobacco under flooding stress.

	Gamma-aminobutyric acid mediates nicotine biosynthesis in tobacco under flooding stress.
	Zhang, Xiaoming; Lin, Hua-Ming; Hu, Hong; Hu, Xiangyang; Hu, Liwei
	2016
发表期刊	Plant diversity
ISSN	2468-2659
卷号	38 期号:1 页码:53-58
摘要	Gamma-aminobutyric acid (GABA) is a four-carbon non-protein amino acid conserved from bacteria to plants and vertebrates. Increasing evidence supports a regulatory role for GABA in plant development and the plant's response to environmental stress. The biosynthesis of nicotine, the main economically important metabolite in tobacco, is tightly regulated. GABA has not hitherto been reported to function in nicotine biosynthesis. Here we report that water flooding treatment (hypoxia) markedly induced the accumulation of GABA and stimulated nicotine biosynthesis. Suppressing GABA accumulation by treatment with glutamate decarboxylase inhibitor impaired flooding-induced nicotine biosynthesis, while exogenous GABA application directly induced nicotine biosynthesis. Based on these results, we propose that GABA triggers nicotine biosynthesis in tobacco seedlings subjected to flooding. Our results provide insight into the molecular mechanism of nicotine biosynthesis in tobacco plants exposed to environmental stress.
文献类型	期刊论文
条目标识符	http://ir.kib.ac.cn/handle/151853/64900
专题	植物化学与西部植物资源持续利用国家重点实验室
推荐引用方式 GB/T 7714	Zhang, Xiaoming,Lin, Hua-Ming,Hu, Hong,et al. Gamma-aminobutyric acid mediates nicotine biosynthesis in tobacco under flooding stress.[J]. Plant diversity,2016,38(1):53-58.
APA	Zhang, Xiaoming,Lin, Hua-Ming,Hu, Hong,Hu, Xiangyang,&Hu, Liwei.(2016).Gamma-aminobutyric acid mediates nicotine biosynthesis in tobacco under flooding stress..Plant diversity,38(1),53-58.
MLA	Zhang, Xiaoming,et al."Gamma-aminobutyric acid mediates nicotine biosynthesis in tobacco under flooding stress.".Plant diversity 38.1(2016):53-58.