Neolignans from Selaginella moellendorffii.
Zhuo, Jing-Xian; Wang, Yue-Hu; Su, Xing-Li; Mei, Ren-Qiang; Yang, Jun; Kong, Yi; Long, Chun-Lin
2016
发表期刊Natural products and bioprospecting
ISSN2192-2195
卷号6期号:3页码:161-6
摘要Two new neolignans selaginellol (1) and selaginellol 4'-O-beta-D-glucopyranoside (2), together with seven known compounds (3-9), were isolated from the whole plant of Selaginella moellendorffii. The structures of the new isolates were determined through spectroscopic data analysis. Compounds 1-9, as well as compounds 10-18 previously isolated from the species, were measured for the activity against platelet aggregation induced by ADP or collagen. Three neoligans (8, 11, and 12), one flavanone (14), and one alkaloid (16) showed inhibitory activity against ADP- or collagen-induced platelet aggregation as compared with tirofiban. The dihydrobenzofuran neolignans (8, 11, and 12) are more potent than the benzofuran neolignan (13) and other types of neolignans (1-7). Glucosidation of the dihydrobenzofuran neolignans (11 and 12) is helpful for the activity. Two new neolignans selaginellol (1) and selaginellol 4'-O-beta-D-glucopyranoside (2) were isolated from the whole plant of Selaginella moellendorffii. Several compounds from this plant showed the activity against platelet aggregation induced by ADP or collagen.
文献类型期刊论文
条目标识符http://ir.kib.ac.cn/handle/151853/64887
专题植物化学与西部植物资源持续利用国家重点实验室
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Zhuo, Jing-Xian,Wang, Yue-Hu,Su, Xing-Li,et al. Neolignans from Selaginella moellendorffii.[J]. Natural products and bioprospecting,2016,6(3):161-6.
APA Zhuo, Jing-Xian.,Wang, Yue-Hu.,Su, Xing-Li.,Mei, Ren-Qiang.,Yang, Jun.,...&Long, Chun-Lin.(2016).Neolignans from Selaginella moellendorffii..Natural products and bioprospecting,6(3),161-6.
MLA Zhuo, Jing-Xian,et al."Neolignans from Selaginella moellendorffii.".Natural products and bioprospecting 6.3(2016):161-6.
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