Abietane Diterpernoids from the Roots of Euphorbia ebracteolata.

KIB OpenIR

	Abietane Diterpernoids from the Roots of Euphorbia ebracteolata.
	Ma, Yuan-Liang; Tang, Xiao-Han; Yuan, Wen-Juan; Ding, Xiao; Di, Ying-Tong; Hao, Xiao-Jiang
	2018
发表期刊	Natural products and bioprospecting
ISSN	2192-2195
卷号	8 期号:2 页码:131-135
摘要	A new ent-abietane diterpernoid, named ebracteolata D (1), along with 11 known analogues, was isolated from the roots of Euphorbia ebracteolata Hayata. The structure of 1 was elucidated on the basis of spectroscopic analysis and molecular modeling. Cytotoxicity of compounds 1-12 was evaluated as well as the effect on the NF-kappaB pathway. Among them, compound 12, jolkinolide B, displayed broad inhibitory effects against proliferation of tumor cell lines. Mechanistic studies indicated that thecompound 12 can inhibit TNF-alpha induced NF-kappaB activation, thereby inducing tumor cell apoptosis.
语种	英语
文献类型	期刊论文
条目标识符	http://ir.kib.ac.cn/handle/151853/64821
专题	中国科学院昆明植物研究所
推荐引用方式 GB/T 7714	Ma, Yuan-Liang,Tang, Xiao-Han,Yuan, Wen-Juan,et al. Abietane Diterpernoids from the Roots of Euphorbia ebracteolata.[J]. Natural products and bioprospecting,2018,8(2):131-135.
APA	Ma, Yuan-Liang,Tang, Xiao-Han,Yuan, Wen-Juan,Ding, Xiao,Di, Ying-Tong,&Hao, Xiao-Jiang.(2018).Abietane Diterpernoids from the Roots of Euphorbia ebracteolata..Natural products and bioprospecting,8(2),131-135.
MLA	Ma, Yuan-Liang,et al."Abietane Diterpernoids from the Roots of Euphorbia ebracteolata.".Natural products and bioprospecting 8.2(2018):131-135.