Amides, Isoquinoline Alkaloids and Dipeptides from the Aerial Parts of Piper mullesua.

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	Amides, Isoquinoline Alkaloids and Dipeptides from the Aerial Parts of Piper mullesua.
	Xia, Meng-Yuan; Yang, Jun; Zhang, Pan-Hua; Li, Xiao-Nian; Luo, Ji-Feng; Long, Chun-Lin; Wang, Yue-Hu
	2018
发表期刊	Natural products and bioprospecting
ISSN	2192-2195
卷号	8 期号:6 页码:419-430
摘要	One undescribed amide, pipermullesine A, two undescribed isoquinoline alkaloids, pipermullesines B and C, and six undescribed dipeptides, pipermullamides A-F, along with 28 known compounds, were isolated from the aerial parts of Piper mullesua. The structures of the undescribed compounds were elucidated based on the analysis of 1D and 2D NMR and MS data. Furthermore, the structures of pipermullesines A-C were confirmed by single crystal X-ray diffraction analysis. All isolates were evaluated for inhibitory activity against platelet aggregation induced by thrombin (IIa) or platelet-activating factor (PAF). (-)-Mangochinine, pellitorine, and (2E,4E)-N-isobutyl-2,4-dodecadienamide showed weak inhibitory activity against rabbit platelet aggregation induced by PAF, with IC50 values of 470.3g/mL, 614.9g/mL, and 579.7g/mL, respectively.
语种	英语
文献类型	期刊论文
条目标识符	http://ir.kib.ac.cn/handle/151853/64781
专题	中国科学院昆明植物研究所
推荐引用方式 GB/T 7714	Xia, Meng-Yuan,Yang, Jun,Zhang, Pan-Hua,et al. Amides, Isoquinoline Alkaloids and Dipeptides from the Aerial Parts of Piper mullesua.[J]. Natural products and bioprospecting,2018,8(6):419-430.
APA	Xia, Meng-Yuan.,Yang, Jun.,Zhang, Pan-Hua.,Li, Xiao-Nian.,Luo, Ji-Feng.,...&Wang, Yue-Hu.(2018).Amides, Isoquinoline Alkaloids and Dipeptides from the Aerial Parts of Piper mullesua..Natural products and bioprospecting,8(6),419-430.
MLA	Xia, Meng-Yuan,et al."Amides, Isoquinoline Alkaloids and Dipeptides from the Aerial Parts of Piper mullesua.".Natural products and bioprospecting 8.6(2018):419-430.