Structurally Diverse Polymethylated Phloroglucinol Meroterpenoids from Baeckea frutescens.

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	Structurally Diverse Polymethylated Phloroglucinol Meroterpenoids from Baeckea frutescens.
	Zhi, Yin-E; Qi, Xu-Jie; Liu, Hui; Zeng, Yuan; Ni, Wei; He, Li; Wang, Zu-Ding; Liu, Hai-Yang
	2018
发表期刊	Natural products and bioprospecting
ISSN	2192-2195
卷号	8 期号:6 页码:431-439
摘要	Phytochemical investigation of the MeOH extract of twigs and leaves of Baeckea frutescens led to the isolation of seven new polymethylated phloroglucinol meroterpenoids (PPMs), named baeckfrutones M-S (1-7). Their structures and absolute configurations were determined by spectroscopic analyses, chiral-phase HPLC analysis, and electronic circular dichroism (ECD) calculations. PPM 1 is a novel meroterpenoid possessing a 6/6/5/3 tetracyclic skeleton in PPMs, whereas 3 and 4 are the first hydroxytasmanone type phloroglucinol-monoterpene hybrids. (+)-2 and 7 displayed potent anti-inflammatory activity with IC50 values of 20.86±0.60 and 36.21±1.18 muMu, respectively.
语种	英语
文献类型	期刊论文
条目标识符	http://ir.kib.ac.cn/handle/151853/64778
专题	中国科学院昆明植物研究所
推荐引用方式 GB/T 7714	Zhi, Yin-E,Qi, Xu-Jie,Liu, Hui,et al. Structurally Diverse Polymethylated Phloroglucinol Meroterpenoids from Baeckea frutescens.[J]. Natural products and bioprospecting,2018,8(6):431-439.
APA	Zhi, Yin-E.,Qi, Xu-Jie.,Liu, Hui.,Zeng, Yuan.,Ni, Wei.,...&Liu, Hai-Yang.(2018).Structurally Diverse Polymethylated Phloroglucinol Meroterpenoids from Baeckea frutescens..Natural products and bioprospecting,8(6),431-439.
MLA	Zhi, Yin-E,et al."Structurally Diverse Polymethylated Phloroglucinol Meroterpenoids from Baeckea frutescens.".Natural products and bioprospecting 8.6(2018):431-439.