Scopariusols L-T, nine new ent-kaurane diterpenoids isolated from Isodon scoparius

KIB OpenIR

	Scopariusols L-T, nine new ent-kaurane diterpenoids isolated from Isodon scoparius
	Jiang Hua-Yi; Li Xiao-Nian; Sun Han-Dong; Zhang Hong-Bin; Puno, Pema-Tenzin
	2018
发表期刊	CHINESE JOURNAL OF NATURAL MEDICINES
ISSN	2095-6975
卷号	16 期号:6 页码:456-464
摘要	Nine new ent-kaurane diterpenoids, named scopariusols L-T (1-9), were isolated from the aerial parts of Isodon scoparius. Their structures were characterized mainly by analyzing the NMR and HR-ESI-MS data, and the absolute configuration of 1 was determined by single-crystal X-ray diffraction. Compound 1 was active against five human tumor cell lines (HL-60, SMMC-7721, A-549, MCF-7, and SW-480), and it also inhibited NO production in LPS-stimulated RAW264.7 cells, with an IC(50 )value of 0.6 mu mol.L-1.
收录类别	SCI
语种	英语
文献类型	期刊论文
条目标识符	http://ir.kib.ac.cn/handle/151853/64733
专题	中国科学院昆明植物研究所
推荐引用方式 GB/T 7714	Jiang Hua-Yi,Li Xiao-Nian,Sun Han-Dong,et al. Scopariusols L-T, nine new ent-kaurane diterpenoids isolated from Isodon scoparius[J]. CHINESE JOURNAL OF NATURAL MEDICINES,2018,16(6):456-464.
APA	Jiang Hua-Yi,Li Xiao-Nian,Sun Han-Dong,Zhang Hong-Bin,&Puno, Pema-Tenzin.(2018).Scopariusols L-T, nine new ent-kaurane diterpenoids isolated from Isodon scoparius.CHINESE JOURNAL OF NATURAL MEDICINES,16(6),456-464.
MLA	Jiang Hua-Yi,et al."Scopariusols L-T, nine new ent-kaurane diterpenoids isolated from Isodon scoparius".CHINESE JOURNAL OF NATURAL MEDICINES 16.6(2018):456-464.