Norascyronones A and B, 2,3,4-nor-Polycyclic Polyprenylated Acylphloroglucinols from Hypericum ascyron
Hu, Ya-Li1,2,3; Hu, Kun1,2; Kong, Ling-Mei1,2,3; Xia, Fan1,2,3; Yang, Xing-Wei1,2; Xu, Gang1,2
2019-02-15
Source PublicationORGANIC LETTERS
ISSN1523-7060
Volume21Issue:4Pages:1007-1010
AbstractPhytochemical study of Hypericum ascyron led to the characterization of norascyronones A-C (1-3), metabolites derived from bicyclic polyprenylated acylphloroglucinols by losing eight carbons (C-2/3/4 of core and the isoprenyl at C-3). Compounds 1/2 with an unprecedented 6/6/5/6 ring system should be generated via [4 + 2] intramolecular cyclization of 3. Their structures were determined by spectroscopic and X-ray diffraction data. Compounds 1 and 2 showed cytotoxicities against the SK-BR-3 cell line (IC50 4.3 and 7.8 mu M).
Indexed BySCI
Language英语
Document Type期刊论文
Identifierhttp://ir.kib.ac.cn/handle/151853/64641
Collection植物化学与西部植物资源持续利用国家重点实验室
Corresponding AuthorYang, Xing-Wei; Xu, Gang
Affiliation1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Yunnan, Peoples R China
2.Yunnan Key Lab Nat Med Chem, Kunming 650201, Yunnan, Peoples R China
3.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
Recommended Citation
GB/T 7714
Hu, Ya-Li,Hu, Kun,Kong, Ling-Mei,et al. Norascyronones A and B, 2,3,4-nor-Polycyclic Polyprenylated Acylphloroglucinols from Hypericum ascyron[J]. ORGANIC LETTERS,2019,21(4):1007-1010.
APA Hu, Ya-Li,Hu, Kun,Kong, Ling-Mei,Xia, Fan,Yang, Xing-Wei,&Xu, Gang.(2019).Norascyronones A and B, 2,3,4-nor-Polycyclic Polyprenylated Acylphloroglucinols from Hypericum ascyron.ORGANIC LETTERS,21(4),1007-1010.
MLA Hu, Ya-Li,et al."Norascyronones A and B, 2,3,4-nor-Polycyclic Polyprenylated Acylphloroglucinols from Hypericum ascyron".ORGANIC LETTERS 21.4(2019):1007-1010.
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