Five new alkaloids from Aconitum apetalum (Ranunculaceae)
Hu, Zhan-Xing1,2,3,4,5,6; Tang, Hong-Yu2,7; Yan, Xiao-Hui8; Zeng, Yan-Rong4,5,6; Aisa, Haji Aker1; Zhang, Yu2; Hao, Xiao-Jiang2,4,5,6
AbstractTwenty-one alkaloids, including five new ones, acoapetaldines A-E (1-5), were isolated from the whole plants of Aconitum apetalum. Among them, 1 is an aconitine-type diterpenoid alkaloid, 2 and 3 are aporphine alkaloids and 4 and 5 are napelline-type diterpenoid alkaloids. The structures of the new alkaloids were elucidated by spectroscopic data analysis and that of acoapetaldine D (4) was confirmed by single crystal X-ray crystallography. Acoapetaldine A (1) and aconorine (12) exhibited moderate anti-tobacco mosaic virus (anti-TMV) activity, while corydine (15) displayed moderate antimicrobial activity against Pseudomonas aeruginosa.
KeywordAconitum apetalum Diterpenoid alkaloids Aporphine alkaloids Anti-TMV Antimicrobial
Indexed BySCI
Document Type期刊论文
Corresponding AuthorZhang, Yu; Hao, Xiao-Jiang
Affiliation1.Chinese Acad Sci, Xinjiang Tech Inst Phys & Chem, Urumqi 830011, Peoples R China
2.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Yunnan, Peoples R China
3.Univ Chinese Acad Sci, Yuquan Rd 19, Beijing 100049, Peoples R China
4.Guizhou Med Univ, State Key Lab Funct & Applicat Med Plants, Guiyang 550014, Guizhou, Peoples R China
5.Key Lab Chem Nat Prod Guizhou Prov, Guiyang 550002, Guizhou, Peoples R China
6.Chinese Acad Sci, Guiyang 550002, Guizhou, Peoples R China
7.Yunnan Univ, Sch Chem Sci & Technol, Kunming 650091, Yunnan, Peoples R China
8.Southwest Forestry Univ, Coll Forestry, Key Lab Forest Disaster Warning & Control Yunnan, Kunming 650224, Yunnan, Peoples R China
Recommended Citation
GB/T 7714
Hu, Zhan-Xing,Tang, Hong-Yu,Yan, Xiao-Hui,et al. Five new alkaloids from Aconitum apetalum (Ranunculaceae)[J]. PHYTOCHEMISTRY LETTERS,2019,29:6-11.
APA Hu, Zhan-Xing.,Tang, Hong-Yu.,Yan, Xiao-Hui.,Zeng, Yan-Rong.,Aisa, Haji Aker.,...&Hao, Xiao-Jiang.(2019).Five new alkaloids from Aconitum apetalum (Ranunculaceae).PHYTOCHEMISTRY LETTERS,29,6-11.
MLA Hu, Zhan-Xing,et al."Five new alkaloids from Aconitum apetalum (Ranunculaceae)".PHYTOCHEMISTRY LETTERS 29(2019):6-11.
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