Thiodiketopiperazines Produced by Penicillium crustosum and Their Activities to Promote Gastrointestinal Motility | |
He, Xin1; Yang, Jing2; Qiu, Ling1; Feng, Dan1; Ju, Feng1; Tan, Lu1; Li, Yu-Zhi1; Gu, Yu-Cheng3; Zhang, Zhen1; Guo, Da-Le1; Deng, Yun1 | |
2019-01-02 | |
发表期刊 | MOLECULES |
ISSN | 1420-3049 |
卷号 | 24期号:2页码:8 |
摘要 | Three new thiodiketopiperazines (1-3), along with two known analogues (4 and 5), were isolated from the fermentation broth of Penicillium crustosum. Their structures were elucidated through extensive spectroscopic analysis and the absolute configurations of new compounds were determined by Mosher ester analysis and calculated ECD spectra. Compound 4 and 5 have the activity to promote the gastrointestinal motility of zebrafish via acting on the cholinergic nervous system. |
关键词 | Penicillium crustosum Isaria cicadae thiodiketopiperazines Mosher analysis ECD calculation gastrointestinal motility |
收录类别 | SCI |
语种 | 英语 |
文献类型 | 期刊论文 |
条目标识符 | http://ir.kib.ac.cn/handle/151853/64428 |
专题 | 植物化学与西部植物资源持续利用国家重点实验室 |
通讯作者 | Guo, Da-Le; Deng, Yun |
作者单位 | 1.Chengdu Univ Tradit Chinese Med, Breeding Base Systemat Res Dev & Utilizat Chinese, Key Lab Standardizat Chinese Herbal Med, Minist Educ,State Key Lab,Sch Pharm, Chengdu 611137, Sichuan, Peoples R China 2.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Yunnan, Peoples R China 3.Syngenta Jealotts Hill Int Res Ctr, Bracknell RG42 6EY, Berks, England |
推荐引用方式 GB/T 7714 | He, Xin,Yang, Jing,Qiu, Ling,et al. Thiodiketopiperazines Produced by Penicillium crustosum and Their Activities to Promote Gastrointestinal Motility[J]. MOLECULES,2019,24(2):8. |
APA | He, Xin.,Yang, Jing.,Qiu, Ling.,Feng, Dan.,Ju, Feng.,...&Deng, Yun.(2019).Thiodiketopiperazines Produced by Penicillium crustosum and Their Activities to Promote Gastrointestinal Motility.MOLECULES,24(2),8. |
MLA | He, Xin,et al."Thiodiketopiperazines Produced by Penicillium crustosum and Their Activities to Promote Gastrointestinal Motility".MOLECULES 24.2(2019):8. |
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