Thiodiketopiperazines Produced by Penicillium crustosum and Their Activities to Promote Gastrointestinal Motility
He, Xin1; Yang, Jing2; Qiu, Ling1; Feng, Dan1; Ju, Feng1; Tan, Lu1; Li, Yu-Zhi1; Gu, Yu-Cheng3; Zhang, Zhen1; Guo, Da-Le1; Deng, Yun1
2019-01-02
Source PublicationMOLECULES
ISSN1420-3049
Volume24Issue:2Pages:8
AbstractThree new thiodiketopiperazines (1-3), along with two known analogues (4 and 5), were isolated from the fermentation broth of Penicillium crustosum. Their structures were elucidated through extensive spectroscopic analysis and the absolute configurations of new compounds were determined by Mosher ester analysis and calculated ECD spectra. Compound 4 and 5 have the activity to promote the gastrointestinal motility of zebrafish via acting on the cholinergic nervous system.
KeywordPenicillium crustosum Isaria cicadae thiodiketopiperazines Mosher analysis ECD calculation gastrointestinal motility
Indexed BySCI
Language英语
Document Type期刊论文
Identifierhttp://ir.kib.ac.cn/handle/151853/64428
Collection植物化学与西部植物资源持续利用国家重点实验室
Corresponding AuthorGuo, Da-Le; Deng, Yun
Affiliation1.Chengdu Univ Tradit Chinese Med, Breeding Base Systemat Res Dev & Utilizat Chinese, Key Lab Standardizat Chinese Herbal Med, Minist Educ,State Key Lab,Sch Pharm, Chengdu 611137, Sichuan, Peoples R China
2.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Yunnan, Peoples R China
3.Syngenta Jealotts Hill Int Res Ctr, Bracknell RG42 6EY, Berks, England
Recommended Citation
GB/T 7714
He, Xin,Yang, Jing,Qiu, Ling,et al. Thiodiketopiperazines Produced by Penicillium crustosum and Their Activities to Promote Gastrointestinal Motility[J]. MOLECULES,2019,24(2):8.
APA He, Xin.,Yang, Jing.,Qiu, Ling.,Feng, Dan.,Ju, Feng.,...&Deng, Yun.(2019).Thiodiketopiperazines Produced by Penicillium crustosum and Their Activities to Promote Gastrointestinal Motility.MOLECULES,24(2),8.
MLA He, Xin,et al."Thiodiketopiperazines Produced by Penicillium crustosum and Their Activities to Promote Gastrointestinal Motility".MOLECULES 24.2(2019):8.
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