Among many traditional medicines, Ganoderma has been used in Asian countries for over two millennia as a traditional medicine for maintaining vivacity and longevity. Research on various metabolic activities of Ganoderma have been performed both in vitro and in vivo studies. However, it is debatable whether Ganoderma is a food supplement for health maintenance or a therapeutic "drug" for medical purposes. Over the past two decades, the Ganoderma industry has developed greatly and today offers thousands of products to the markets. Despite the large market, there are problems with the industry which prevent it from establishing an effective market. This paper describes the current status of the world Ganoderma cultivation, products, industry and provides suggestions for facilitating further research.