Antibacterial Indole Alkaloids with Complex Heterocycles from Voacanga africana

doi:10.1021/acs.orglett.8b00913

KIB OpenIR > 离退休

	Antibacterial Indole Alkaloids with Complex Heterocycles from Voacanga africana
	Ding, Cai-Feng1,2 ; Ma, Hong-Xia 3; Yang, Jing1 ; Qin, Xu-Jie1 ; Njateng, Guy S. S.4; Yu, Hao-Fei 1,2; Wei, Xin 1,2; Liu, Ya-Ping 1; Huang, Wan-Yi 3; Yang, Zi-Feng 3; Wang, Xin-Hua 3; Luo, Xiao-Dong1,3
	2018-05-04
发表期刊	ORGANIC LETTERS
ISSN	1523-7060
卷号	20 期号:9 页码:2702-2706
摘要	Voacafricines A and B, two unique mono-terpenoid indole alkaloids each bearing five fused heterocycles, were obtained from the fruits of Voacanga africana. Their structures were elucidated by extensive spectroscopic methods and computational studies. A plausible biogenetic pathway was proposed from a common precursor, 19-epi-voacristine. Both compounds exhibited potent activity against Staphylococcus aureus and Salmonella typhi, and their activities were superior to those of the well-known antibacterial drugs berberine and fibrauretine.
DOI	10.1021/acs.orglett.8b00913
语种	英语
引用统计
文献类型	期刊论文
条目标识符	http://ir.kib.ac.cn/handle/151853/61341
专题	离退休
作者单位	1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Yunnan, Peoples R China 2.Chinese Acad Sci, Grad Univ, Beijing 100049, Peoples R China 3.Guangzhou Med Univ, State Key Lab Resp Dis, Guangzhou 510120, Guangdong, Peoples R China 4.Univ Dschang, Fac Sci, Dept Biochem, POB 67, Dschang, Cameroon
推荐引用方式 GB/T 7714	Ding, Cai-Feng,Ma, Hong-Xia,Yang, Jing,et al. Antibacterial Indole Alkaloids with Complex Heterocycles from Voacanga africana[J]. ORGANIC LETTERS,2018,20(9):2702-2706.
APA	Ding, Cai-Feng.,Ma, Hong-Xia.,Yang, Jing.,Qin, Xu-Jie.,Njateng, Guy S. S..,...&Luo, Xiao-Dong.(2018).Antibacterial Indole Alkaloids with Complex Heterocycles from Voacanga africana.ORGANIC LETTERS,20(9),2702-2706.
MLA	Ding, Cai-Feng,et al."Antibacterial Indole Alkaloids with Complex Heterocycles from Voacanga africana".ORGANIC LETTERS 20.9(2018):2702-2706.