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Antibacterial Indole Alkaloids with Complex Heterocycles from Voacanga africana
Ding, Cai-Feng1,2; Ma, Hong-Xia3; Yang, Jing1; Qin, Xu-Jie1; Njateng, Guy S. S.4; Yu, Hao-Fei1,2; Wei, Xin1,2; Liu, Ya-Ping1; Huang, Wan-Yi3; Yang, Zi-Feng3; Wang, Xin-Hua3; Luo, Xiao-Dong1,3
2018-05-04
Source PublicationORGANIC LETTERS
ISSN1523-7060
Volume20Issue:9Pages:2702-2706
AbstractVoacafricines A and B, two unique mono-terpenoid indole alkaloids each bearing five fused heterocycles, were obtained from the fruits of Voacanga africana. Their structures were elucidated by extensive spectroscopic methods and computational studies. A plausible biogenetic pathway was proposed from a common precursor, 19-epi-voacristine. Both compounds exhibited potent activity against Staphylococcus aureus and Salmonella typhi, and their activities were superior to those of the well-known antibacterial drugs berberine and fibrauretine.
DOI10.1021/acs.orglett.8b00913
Language英语
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Cited Times:22[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://ir.kib.ac.cn/handle/151853/61341
Collection离退休
Affiliation1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Yunnan, Peoples R China
2.Chinese Acad Sci, Grad Univ, Beijing 100049, Peoples R China
3.Guangzhou Med Univ, State Key Lab Resp Dis, Guangzhou 510120, Guangdong, Peoples R China
4.Univ Dschang, Fac Sci, Dept Biochem, POB 67, Dschang, Cameroon
Recommended Citation
GB/T 7714
Ding, Cai-Feng,Ma, Hong-Xia,Yang, Jing,et al. Antibacterial Indole Alkaloids with Complex Heterocycles from Voacanga africana[J]. ORGANIC LETTERS,2018,20(9):2702-2706.
APA Ding, Cai-Feng.,Ma, Hong-Xia.,Yang, Jing.,Qin, Xu-Jie.,Njateng, Guy S. S..,...&Luo, Xiao-Dong.(2018).Antibacterial Indole Alkaloids with Complex Heterocycles from Voacanga africana.ORGANIC LETTERS,20(9),2702-2706.
MLA Ding, Cai-Feng,et al."Antibacterial Indole Alkaloids with Complex Heterocycles from Voacanga africana".ORGANIC LETTERS 20.9(2018):2702-2706.
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