| Characterization of Sesquiterpene Dimers from Resina Commiphora That Promote Adipose-Derived Stem Cell Proliferation and Differentiation | |
| Liu, Jia-Wang1,4; Zhang, Min-Yu2; Yan, Yong-Min2; Wei, Xiao-Yi5; Dong, Lu1; Zhu, Yan-Xia2; Cheng, Yong-Xian1,2,3 | |
| 2018-03-02 | |
| 发表期刊 | JOURNAL OF ORGANIC CHEMISTRY
 |
| ISSN | 0022-3263 |
| 卷号 | 83期号:5页码:2725-2733 |
| 摘要 | The new sesquiterpene dimers commiphoroids A-D (1-4) were isolated from Resina Commiphora, and their structures were assigned by spectroscopic methods and X-ray diffraction analysis. Compounds 1 and 2 are stereoisomers of putative [2 + 4]-cycloaddition reactions, and 3 is a trinorsesquiterpene dimer containing a 6/6/5/6/6/6 hexacyclic framework, while 4 possesses a 8-oxabicyclo[3.2.1]oct-6-ene skeletal core. Plausible biosynthetic pathways for 1-4 are proposed. Biochemical studies show that compound 1 promotes ca. 60% expression of keratinocyte-specific markers in adipose derived stem cells at 10 mu M. |
| DOI | 10.1021/acs.joc.7b03182 |
| 语种 | 英语 |
| WOS记录号 | WOS:000426803300022 |
| 引用统计 | |
| 文献类型 | 期刊论文 |
| 条目标识符 | http://ir.kib.ac.cn/handle/151853/60528 |
| 专题 | 植物化学与西部植物资源持续利用国家重点实验室 |
| 作者单位 | 1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Yunnan, Peoples R China 2.Shenzhen Univ, Guangdong Key Lab Genome Stabil & Dis Prevent, Sch Pharmaceut Sci,Hlth Sci Ctr, Shenzhen Key Lab Antiaging & Regenerat Med,Dept C, Shenzhen 518060, Peoples R China 3.Henan Univ Chinese Med, Zhengzhou 450008, Henan, Peoples R China 4.Univ Chinese Acad Sci, Beijing 100049, Peoples R China 5.South China Bot Garden, Key Lab Plant Resources Conservat & Sustainable U, Guangzhou 510650, Guangdong, Peoples R China |
| 推荐引用方式 GB/T 7714 | Liu, Jia-Wang,Zhang, Min-Yu,Yan, Yong-Min,et al. Characterization of Sesquiterpene Dimers from Resina Commiphora That Promote Adipose-Derived Stem Cell Proliferation and Differentiation[J]. JOURNAL OF ORGANIC CHEMISTRY,2018,83(5):2725-2733. |
| APA | Liu, Jia-Wang.,Zhang, Min-Yu.,Yan, Yong-Min.,Wei, Xiao-Yi.,Dong, Lu.,...&Cheng, Yong-Xian.(2018).Characterization of Sesquiterpene Dimers from Resina Commiphora That Promote Adipose-Derived Stem Cell Proliferation and Differentiation.JOURNAL OF ORGANIC CHEMISTRY,83(5),2725-2733. |
| MLA | Liu, Jia-Wang,et al."Characterization of Sesquiterpene Dimers from Resina Commiphora That Promote Adipose-Derived Stem Cell Proliferation and Differentiation".JOURNAL OF ORGANIC CHEMISTRY 83.5(2018):2725-2733. |
| 条目包含的文件 | 下载所有文件 | |||||
| 文件名称/大小 | 文献类型 | 版本类型 | 开放类型 | 使用许可 | ||
| liu2018 (1).pdf（3453KB） | 期刊论文 | 作者接受稿 | 开放获取 | CC BY-NC-SA | 浏览 下载 | |
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。
修改评论