Two new carbazole alkaloids from Murraya koenigii | |
Wang, YS; He, HP; Shen, YM; Hong, X; Hao, XJ | |
2003-03-01 | |
发表期刊 | JOURNAL OF NATURAL PRODUCTS |
卷号 | 66期号:3页码:416-418 |
摘要 | Two new carbazole alkaloids named murrayanine (1) and 8,8"-biskoenigine (2) were isolated from Murraya koenigii. The structure elucidations for 1 and 2 were carried out on the basis of 1D and 2D NMR experiments. Compound 1 was a novel carbazole alkaloid with a rare phenylpropanyl. substitution. Compound 2 was a symmetrical dimer of the carbazole alkaloid koenigine and showed antiosteoporotic activity in the CAT-B model with IC50 1.3 mug/mL. The synthesis of 2 from koenigine was carried out through oxidative coupling using a solid state reaction. |
学科领域 | Plant Sciences ; Chemistry, Medicinal ; Pharmacology & Pharmacy |
DOI | 10.1021/np020468a |
收录类别 | SCI ; IC |
语种 | 英语 |
WOS记录号 | WOS:000181923100019 |
引用统计 | |
文献类型 | 期刊论文 |
条目标识符 | http://ir.kib.ac.cn/handle/151853/5166 |
专题 | 植物化学与西部植物资源持续利用国家重点实验室 |
作者单位 | 1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650204, Yunnan, Peoples R China 2.Key Lab Chem Nat Prod Guizhou Prov, Guiyang 550002, Guizhou, Peoples R China 3.Chinese Acad Sci, Guiyang 550002, Guizhou, Peoples R China |
推荐引用方式 GB/T 7714 | Wang, YS,He, HP,Shen, YM,et al. Two new carbazole alkaloids from Murraya koenigii[J]. JOURNAL OF NATURAL PRODUCTS,2003,66(3):416-418. |
APA | Wang, YS,He, HP,Shen, YM,Hong, X,&Hao, XJ.(2003).Two new carbazole alkaloids from Murraya koenigii.JOURNAL OF NATURAL PRODUCTS,66(3),416-418. |
MLA | Wang, YS,et al."Two new carbazole alkaloids from Murraya koenigii".JOURNAL OF NATURAL PRODUCTS 66.3(2003):416-418. |
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