| Hyperisampsins N and O, two new benzoylated phloroglucinol derivatives from Hypericum sampsonii | |
Zhu, Hu-Cheng1; Chen, Chun-Mei1; Zhang, Jin-Wen2; Guo, Yi1; Tan, Dong-Dong1; Wei, Guang-Zheng1; Yang, Jing3 ; Wang, Jian-Ping1; Luo, Zeng-Wei1; Xue, Yong-Bo1; Zhang, Yong-Hui1
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| 2017-05-01 | |
| 发表期刊 | CHINESE CHEMICAL LETTERS
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| 卷号 | 28页码:986-990 |
| 摘要 | Twenty-one benzoylated phloroglucinol derivatives bearing homoadamantyl frameworks were isolated from the aerial parts of Hypericum sampsonii, including two new ones named hyperisampsins N and 0 (1 and 2). The structures of 1 and 2 were elucidated by extensive NMR and mass spectrometric analyses. Their absolute configurations were further determined by using TDDFT ECD calculations. Compounds 2, 7, and 8 were evaluated for their cytotoxic activities against five human cancer cell lines, of which, 2 and 8 exhibited significant cytotoxic activities toward HL-60 cell and moderate activities against others cell lines. (C) 2016 Chinese Chemical Society and Institute of Materia Medica, Chinese Academy of Medical Sciences. Published by Elsevier B.V. All rights reserved. |
| 关键词 | Hyperisampsin Ppaps Ecd Calculation Absolute Configuration |
| DOI | 10.1016/j.cclet.2016.11.014 |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000402444600013 |
| 引用统计 | |
| 文献类型 | 期刊论文 |
| 条目标识符 | http://ir.kib.ac.cn/handle/151853/51362 |
| 专题 | 植物化学与西部植物资源持续利用国家重点实验室 |
| 作者单位 | 1.Huazhong Univ Sci & Technol, Tongji Med Coll, Hubei Key Lab Nat Med Chem & Resource Evaluat, Sch Pharm, Wuhan 430030, Peoples R China 2.Huazhong Univ Sci & Technol, Tongji Med Coll, Tongji Hosp, Wuhan 430030, Peoples R China 3.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650204, Peoples R China |
| 推荐引用方式 GB/T 7714 | Zhu, Hu-Cheng,Chen, Chun-Mei,Zhang, Jin-Wen,et al. Hyperisampsins N and O, two new benzoylated phloroglucinol derivatives from Hypericum sampsonii[J]. CHINESE CHEMICAL LETTERS,2017,28:986-990. |
| APA | Zhu, Hu-Cheng.,Chen, Chun-Mei.,Zhang, Jin-Wen.,Guo, Yi.,Tan, Dong-Dong.,...&Zhang, Yong-Hui.(2017).Hyperisampsins N and O, two new benzoylated phloroglucinol derivatives from Hypericum sampsonii.CHINESE CHEMICAL LETTERS,28,986-990. |
| MLA | Zhu, Hu-Cheng,et al."Hyperisampsins N and O, two new benzoylated phloroglucinol derivatives from Hypericum sampsonii".CHINESE CHEMICAL LETTERS 28(2017):986-990. |
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| 71.pdf（876KB） | 期刊论文 | 作者接受稿 | 开放获取 | CC BY-NC-SA | 浏览 下载 | |
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