Hyperisampsins N and O, two new benzoylated phloroglucinol derivatives from Hypericum sampsonii

doi:10.1016/j.cclet.2016.11.014

	Hyperisampsins N and O, two new benzoylated phloroglucinol derivatives from Hypericum sampsonii
	Zhu, Hu-Cheng 1; Chen, Chun-Mei 1; Zhang, Jin-Wen 2; Guo, Yi 1; Tan, Dong-Dong 1; Wei, Guang-Zheng 1; Yang, Jing3 ; Wang, Jian-Ping 1; Luo, Zeng-Wei 1; Xue, Yong-Bo 1; Zhang, Yong-Hui 1
	2017-05-01
发表期刊	CHINESE CHEMICAL LETTERS
卷号	28 页码:986-990
摘要	Twenty-one benzoylated phloroglucinol derivatives bearing homoadamantyl frameworks were isolated from the aerial parts of Hypericum sampsonii, including two new ones named hyperisampsins N and 0 (1 and 2). The structures of 1 and 2 were elucidated by extensive NMR and mass spectrometric analyses. Their absolute configurations were further determined by using TDDFT ECD calculations. Compounds 2, 7, and 8 were evaluated for their cytotoxic activities against five human cancer cell lines, of which, 2 and 8 exhibited significant cytotoxic activities toward HL-60 cell and moderate activities against others cell lines. (C) 2016 Chinese Chemical Society and Institute of Materia Medica, Chinese Academy of Medical Sciences. Published by Elsevier B.V. All rights reserved.
关键词	Hyperisampsin Ppaps Ecd Calculation Absolute Configuration
DOI	10.1016/j.cclet.2016.11.014
收录类别	SCI
语种	英语
WOS记录号	WOS:000402444600013
引用统计
文献类型	期刊论文
条目标识符	http://ir.kib.ac.cn/handle/151853/51362
专题	植物化学与西部植物资源持续利用国家重点实验室
作者单位	1.Huazhong Univ Sci & Technol, Tongji Med Coll, Hubei Key Lab Nat Med Chem & Resource Evaluat, Sch Pharm, Wuhan 430030, Peoples R China 2.Huazhong Univ Sci & Technol, Tongji Med Coll, Tongji Hosp, Wuhan 430030, Peoples R China 3.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650204, Peoples R China
推荐引用方式 GB/T 7714	Zhu, Hu-Cheng,Chen, Chun-Mei,Zhang, Jin-Wen,et al. Hyperisampsins N and O, two new benzoylated phloroglucinol derivatives from Hypericum sampsonii[J]. CHINESE CHEMICAL LETTERS,2017,28:986-990.
APA	Zhu, Hu-Cheng.,Chen, Chun-Mei.,Zhang, Jin-Wen.,Guo, Yi.,Tan, Dong-Dong.,...&Zhang, Yong-Hui.(2017).Hyperisampsins N and O, two new benzoylated phloroglucinol derivatives from Hypericum sampsonii.CHINESE CHEMICAL LETTERS,28,986-990.
MLA	Zhu, Hu-Cheng,et al."Hyperisampsins N and O, two new benzoylated phloroglucinol derivatives from Hypericum sampsonii".CHINESE CHEMICAL LETTERS 28(2017):986-990.

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