New Acetylenic Acids and Derivatives from the Edible Mushroom Craterellus lutescens (Cantharellaceae)
Huang, Ying1,2,3; Zhang, Shuai-Bing2,3; Chen, He-Ping2,3; Zhao, Zhen-Zhu2,3; Zhou, Zhong-Yu4; Li, Zheng-Hui1; Feng, Tao1; Liu, Ji-Kai1
2017-05-17
Source PublicationJOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
Volume65Issue:19Pages:3835-3841
AbstractThirteen new acetylenic acids and their derivatives, craterellynes G-Q (1, 2, 4-10, 12, 13), 9-epi-craterellyne H (3), and 14-O-ethyl-craterellyne O (11), were isolated from the fruiting bodies of edible mushrooms Craterellus lutescens. The structures of these compounds were identified by various spectroscopic and chemical means. The stereoconfigurations of 1-13 were elucidated by the combination of acetonide formation, J-based configuration analysis, and modified Mosher's method. Craterellyne I exhibited c-ytotoxicities against human cancer strains and inhibition of nitric oxide (NO) production, as well as weak antimicrobial activity against Candida albicans.
KeywordActeylenic Acids Mushroom Craterellus Lutescens Craterellynes Cytotoxicity
DOI10.1021/acs.jafc.7b00899
Indexed BySCI
Language英语
WOS IDWOS:000401782300007
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Cited Times:10[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://ir.kib.ac.cn/handle/151853/51229
Collection植物化学与西部植物资源持续利用国家重点实验室
Affiliation1.South Cent Univ Nationalities, Sch Pharmaceut Sci, Wuhan 430074, Peoples R China
2.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Peoples R China
3.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
4.Chinese Acad Sci, South China Bot Garden, Key Lab Plant Resources Conservat & Sustainable U, Guangzhou 510650, Guangdong, Peoples R China
Recommended Citation
GB/T 7714
Huang, Ying,Zhang, Shuai-Bing,Chen, He-Ping,et al. New Acetylenic Acids and Derivatives from the Edible Mushroom Craterellus lutescens (Cantharellaceae)[J]. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY,2017,65(19):3835-3841.
APA Huang, Ying.,Zhang, Shuai-Bing.,Chen, He-Ping.,Zhao, Zhen-Zhu.,Zhou, Zhong-Yu.,...&Liu, Ji-Kai.(2017).New Acetylenic Acids and Derivatives from the Edible Mushroom Craterellus lutescens (Cantharellaceae).JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY,65(19),3835-3841.
MLA Huang, Ying,et al."New Acetylenic Acids and Derivatives from the Edible Mushroom Craterellus lutescens (Cantharellaceae)".JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY 65.19(2017):3835-3841.
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