Ir-Catalyzed Asymmetric Total Synthesis of (-)-Communesin F

doi:10.1021/jacs.7b00854

	Ir-Catalyzed Asymmetric Total Synthesis of (-)-Communesin F
	Liang, Xiao 1,2; Zhang, Tian-Yuan 1,2; Zeng, Xue-Yi 1; Zheng, Yu 1,2; Wei, Kun 1; Yang, Yu-Rong1
	2017-03-08
发表期刊	JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
卷号	139 期号:9 页码:3364-3367
摘要	The first catalytic asymmetric total synthesis of the heptacyclic alkaloid (-)-communesin F is described. A key step features an iridium-catalyzed asymmetric intermolecular cascade cyclization, constructing the lower N,N-aminal-containing CDEF tetracyclic core in one step. Another notable element is the closure of final ring system (A ring) via a facile reduction of a twisted amide and concomitant cyclization activated by mesylation of N,O-hemiaminal intermediate.
DOI	10.1021/jacs.7b00854
收录类别	SCI
语种	英语
WOS记录号	WOS:000396185700015
引用统计
文献类型	期刊论文
条目标识符	http://ir.kib.ac.cn/handle/151853/50996
专题	植物化学与西部植物资源持续利用国家重点实验室
作者单位	1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Peoples R China 2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
推荐引用方式 GB/T 7714	Liang, Xiao,Zhang, Tian-Yuan,Zeng, Xue-Yi,et al. Ir-Catalyzed Asymmetric Total Synthesis of (-)-Communesin F[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY,2017,139(9):3364-3367.
APA	Liang, Xiao,Zhang, Tian-Yuan,Zeng, Xue-Yi,Zheng, Yu,Wei, Kun,&Yang, Yu-Rong.(2017).Ir-Catalyzed Asymmetric Total Synthesis of (-)-Communesin F.JOURNAL OF THE AMERICAN CHEMICAL SOCIETY,139(9),3364-3367.
MLA	Liang, Xiao,et al."Ir-Catalyzed Asymmetric Total Synthesis of (-)-Communesin F".JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 139.9(2017):3364-3367.

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