Isolation and identification of antioxidant and alpha-glucosidase inhibitory compounds from fruit juice of Nitraria tangutorum

doi:10.1016/j.foodchem.2017.01.031

	Isolation and identification of antioxidant and alpha-glucosidase inhibitory compounds from fruit juice of Nitraria tangutorum
	Zhao, Jian-Qiang 1; Wang, Yan-Ming 2,3; Yang, Yan-Long4 ; Zeng, Ying4 ; Wang, Qi-Lan 1; Shao, Yun 1; Mei, Li-Juan 1; Shi, Yan-Ping 2,3; Tao, Yan-Duo 1
	2017-07-15
发表期刊	FOOD CHEMISTRY
卷号	227 期号:1 页码:93-101
摘要	Nitraria tangutorum Bor., having edible berries, is valued for reputed health benefits in Qinghai-Tibet plateau. The phytochemical research on the fruit juice of N. tangutorum led to the isolation of twenty-six compounds including five new compounds, tangutorids A-D (1, 2, 3a, and 3b), and (3E,5E)-7-O-beta-gluco syl-4-(2-methoxy-2-oxoethyl)hepta-3,5-dienoic acid (15). The structures of these compounds were elucidated through comprehensive spectroscopic analyses. Tangutorids A-F were the first examples of glucose-derived beta-carbolines from natural products. The biogenetic pathways of 1-8 were proposed to involve Pictet-Spengler reactions and described starting from the co-isolated tryptophan (10) and corresponding aldehydes. All isolates were evaluated for their antioxidant and alpha-glucosidase inhibitory activities. Compounds 21, 22, and 24 showed antioxidant activity with SC50 values ranging from 12.2 +/- 1.9 to 30.4 +/- 2.7 mu g/mL, and compound 1 showed strong alpha-glucosidase inhibitory effect with IC50 value of 63.3 +/- 4.6 mu g/mL. (C) 2017 Elsevier Ltd. All rights reserved.
关键词	Nitraria Tangutorum Glucose-derived Beta-carbolines Antioxidants Alpha-glucosidase Inhibitory
DOI	10.1016/j.foodchem.2017.01.031
收录类别	SCI
语种	英语
WOS记录号	WOS:000396957100013
引用统计	被引频次：59[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.kib.ac.cn/handle/151853/50993
专题	植物化学与西部植物资源持续利用国家重点实验室
作者单位	1.Chinese Acad Sci, Northwest Inst Plateau Biol, Key Lab Tibetan Med Res, Xining 810008, Peoples R China 2.Chinese Acad Sci, Lanzhou Inst Chem Phys, Key Lab Chem Northwestern Plant Resources, Lanzhou 730000, Peoples R China 3.Chinese Acad Sci, Lanzhou Inst Chem Phys, Key Lab Nat Med Gansu Prov, Lanzhou 730000, Peoples R China 4.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650204, Peoples R China
推荐引用方式 GB/T 7714	Zhao, Jian-Qiang,Wang, Yan-Ming,Yang, Yan-Long,et al. Isolation and identification of antioxidant and alpha-glucosidase inhibitory compounds from fruit juice of Nitraria tangutorum[J]. FOOD CHEMISTRY,2017,227(1):93-101.
APA	Zhao, Jian-Qiang.,Wang, Yan-Ming.,Yang, Yan-Long.,Zeng, Ying.,Wang, Qi-Lan.,...&Tao, Yan-Duo.(2017).Isolation and identification of antioxidant and alpha-glucosidase inhibitory compounds from fruit juice of Nitraria tangutorum.FOOD CHEMISTRY,227(1),93-101.
MLA	Zhao, Jian-Qiang,et al."Isolation and identification of antioxidant and alpha-glucosidase inhibitory compounds from fruit juice of Nitraria tangutorum".FOOD CHEMISTRY 227.1(2017):93-101.

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