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题名: Isolation and identification of antioxidant and alpha-glucosidase inhibitory compounds from fruit juice of Nitraria tangutorum
作者: Zhao, Jian-Qiang1; Wang, Yan-Ming2, 3; Yang, Yan-Long4; Zeng, Ying4; Wang, Qi-Lan1; Shao, Yun1; Mei, Li-Juan1; Shi, Yan-Ping2, 3; Tao, Yan-Duo1
刊名: FOOD CHEMISTRY
关键词: Nitraria tangutorum ; Glucose-derived beta-carbolines ; Antioxidants ; alpha-Glucosidase inhibitory
英文摘要: Nitraria tangutorum Bor., having edible berries, is valued for reputed health benefits in Qinghai-Tibet plateau. The phytochemical research on the fruit juice of N. tangutorum led to the isolation of twenty-six compounds including five new compounds, tangutorids A-D (1, 2, 3a, and 3b), and (3E,5E)-7-O-beta-gluco syl-4-(2-methoxy-2-oxoethyl)hepta-3,5-dienoic acid (15). The structures of these compounds were elucidated through comprehensive spectroscopic analyses. Tangutorids A-F were the first examples of glucose-derived beta-carbolines from natural products. The biogenetic pathways of 1-8 were proposed to involve Pictet-Spengler reactions and described starting from the co-isolated tryptophan (10) and corresponding aldehydes. All isolates were evaluated for their antioxidant and alpha-glucosidase inhibitory activities. Compounds 21, 22, and 24 showed antioxidant activity with SC50 values ranging from 12.2 +/- 1.9 to 30.4 +/- 2.7 mu g/mL, and compound 1 showed strong alpha-glucosidase inhibitory effect with IC50 value of 63.3 +/- 4.6 mu g/mL. (C) 2017 Elsevier Ltd. All rights reserved.
出版日期: 2017-07-15
卷号: 227, 期号:1, 页码:93-101
语种: 英语
收录类别: SCI
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内容类型: 期刊论文
URI标识: http://ir.kib.ac.cn/handle/151853/50993
Appears in Collections:植物化学与西部植物资源持续利用国家重点实验室_期刊论文

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作者单位: 1.Chinese Acad Sci, Northwest Inst Plateau Biol, Key Lab Tibetan Med Res, Xining 810008, Peoples R China
2.Chinese Acad Sci, Lanzhou Inst Chem Phys, Key Lab Chem Northwestern Plant Resources, Lanzhou 730000, Peoples R China
3.Chinese Acad Sci, Lanzhou Inst Chem Phys, Key Lab Nat Med Gansu Prov, Lanzhou 730000, Peoples R China
4.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650204, Peoples R China

Recommended Citation:
Zhao, Jian-Qiang,Wang, Yan-Ming,Yang, Yan-Long,et al. Isolation and identification of antioxidant and alpha-glucosidase inhibitory compounds from fruit juice of Nitraria tangutorum[J]. FOOD CHEMISTRY,2017,227(1):93-101.
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