Indole Alkaloids from the Leaves of Rauvolfia yunnanensis

	Indole Alkaloids from the Leaves of Rauvolfia yunnanensis
	Geng Chang-An 1,2; Liu Xi-Kui 1
	2010-04-10
发表期刊	CHEMICAL JOURNAL OF CHINESE UNIVERSITIES-CHINESE
卷号	31 期号:4 页码:731-735
摘要	Rauvolfia yuananensis Tsiang are commonly used as a folklore herb to treat hypertension, snake bites, and insanity in the southwest of China, and an important industrial raw material of reserpine and vertical. But the wild resources of it reduced gradually in recent years, thus we have introduced and cultivated it to the arid-hot valley region of Yunnan Province, China, and investigated the chemical constituents variety of it for the sustainable utilization. The dried leaves powder (8.0 kg) of R. yunnanensis was extracted with 95% (volume fraction) EtOH(40 L x5, 8 h each), and led to the isolation of eleven indole alkaloids by column chromatography (silica, alumina and Sephadex LH-20 gel) methods. Their structures were identified as caberine (1), 19-ethoxyl-demethyl-Delta'-17-acetylajmaline(2), vellosimine(3), beta-yohimbine(4), yohimbine(5), vinorine(6), picrinine(7), nareline (8), akuammicine(9), strictamine(10), reserpine(11) by spectral analysis (UV, IR, MS and 1 D, 2D NMR), respectively. Among them, compound 2 was a new indole alkaloids, compounds 1, 8 and 9 were firstly isolated from this plant.
关键词	Rauvolfia Yunnanensis Indole Alkaloid 19-ethoxyl-1-demethyl-delta '-acetylajmaline Caberine Reserpine Yohimbine
学科领域	Chemistry, Multidisciplinary
收录类别	SCI
语种	英语
WOS记录号	WOS:000277223700022
引用统计
文献类型	期刊论文
条目标识符	http://ir.kib.ac.cn/handle/151853/5038
专题	植物化学与西部植物资源持续利用国家重点实验室
作者单位	1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650204, Peoples R China 2.Chinese Acad Sci, Grad Sch, Beijing 100049, Peoples R China
推荐引用方式 GB/T 7714	Geng Chang-An,Liu Xi-Kui. Indole Alkaloids from the Leaves of Rauvolfia yunnanensis[J]. CHEMICAL JOURNAL OF CHINESE UNIVERSITIES-CHINESE,2010,31(4):731-735.
APA	Geng Chang-An,&Liu Xi-Kui.(2010).Indole Alkaloids from the Leaves of Rauvolfia yunnanensis.CHEMICAL JOURNAL OF CHINESE UNIVERSITIES-CHINESE,31(4),731-735.
MLA	Geng Chang-An,et al."Indole Alkaloids from the Leaves of Rauvolfia yunnanensis".CHEMICAL JOURNAL OF CHINESE UNIVERSITIES-CHINESE 31.4(2010):731-735.

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