Diterpenoids from Isodon melissoides
Zhao, AH; Han, QB; Li, RT; Li, SH; Qing, C; Zhang, YL; Zhao, QS; Wang, FS; Sun, HD
2004-09-01
发表期刊JOURNAL OF NATURAL PRODUCTS
ISSN0163-3864
卷号67期号:9页码:1441-1444
摘要Nine new diterpenoids, melissoidesins M-U (1-9), along with five known analogues, melissoidesin F (10), xindongnin B (11), melissoidesin G (12), melissoidesin E (13), and dawoensin A (14), were isolated from the aerial parts of Isodon melissoides. The structures of new compounds were elucidated by analysis of spectral evidence including extensive 2D NMR data. Compounds 2, 3, 7, 11, 12, and 14 showed cytotoxicity against the human tumor BGC-823 cell line with IC50 values less than 10 mug/mL, respectively.
关键词Isodon Melissoides Labiatae Ent-kaurane Diterpenoids Melissoidesin A-d
学科领域Plant Sciences ; Chemistry, Medicinal ; Pharmacology & Pharmacy
DOI10.1021/np030418l
收录类别SCI ; IC
语种英语
WOS记录号WOS:000224187700002
引用统计
文献类型期刊论文
条目标识符http://ir.kib.ac.cn/handle/151853/4646
专题植物化学与西部植物资源持续利用国家重点实验室
作者单位1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650204, Peoples R China
2.Shanghai Jiao Tong Univ, Sch Pharm, Shanghai 200030, Peoples R China
3.Kunming Med Coll, Yunnan Key Lab Pharmacol Nat Prod, Kunming 650031, Peoples R China
4.Dali Med Coll, Dept Pharmacol, Dalian 671000, Peoples R China
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GB/T 7714
Zhao, AH,Han, QB,Li, RT,et al. Diterpenoids from Isodon melissoides[J]. JOURNAL OF NATURAL PRODUCTS,2004,67(9):1441-1444.
APA Zhao, AH.,Han, QB.,Li, RT.,Li, SH.,Qing, C.,...&Sun, HD.(2004).Diterpenoids from Isodon melissoides.JOURNAL OF NATURAL PRODUCTS,67(9),1441-1444.
MLA Zhao, AH,et al."Diterpenoids from Isodon melissoides".JOURNAL OF NATURAL PRODUCTS 67.9(2004):1441-1444.
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