Ganotheaecolin A, a Neurotrophic Conjugated Ergosterol with a Naphtho[1,8-ef]azulene Scaffold from Ganoderma theaecolum
Luo, Qi1,3; Yang, Zhu-Liang2; Yan, Yong-Ming1; Cheng, Yong-Xian1
2017-02-03
发表期刊ORGANIC LETTERS
卷号19期号:3页码:718-721
摘要Ganotheaecolin A (1), a novel ergosterol with a rare naphtho[1,8-ef]azulene ring system, was isolated from the fruiting bodies of Ganoderma theaecolum. Its structure was determined by spectroscopic data and computational methods. Compound 1 represents a 6/6/7/5-fused carbon skeletal ergosterol typically formed by Wagner-Meerwein rearrangement, whose plausible biosynthetic pathway was briefly discussed. Finally, the neurotrophic activity of 1 was examined using PC12 cells.
DOI10.1021/acs.orglett.7b00012
收录类别SCI
语种英语
WOS记录号WOS:000393539900074
引用统计
文献类型期刊论文
条目标识符http://ir.kib.ac.cn/handle/151853/46035
专题植物化学与西部植物资源持续利用国家重点实验室
作者单位1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Peoples R China
2.Chinese Acad Sci, Kunming Inst Bot, Key Lab Plant Divers & Biogeog East Asia, Kunming 650201, Peoples R China
3.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
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GB/T 7714
Luo, Qi,Yang, Zhu-Liang,Yan, Yong-Ming,et al. Ganotheaecolin A, a Neurotrophic Conjugated Ergosterol with a Naphtho[1,8-ef]azulene Scaffold from Ganoderma theaecolum[J]. ORGANIC LETTERS,2017,19(3):718-721.
APA Luo, Qi,Yang, Zhu-Liang,Yan, Yong-Ming,&Cheng, Yong-Xian.(2017).Ganotheaecolin A, a Neurotrophic Conjugated Ergosterol with a Naphtho[1,8-ef]azulene Scaffold from Ganoderma theaecolum.ORGANIC LETTERS,19(3),718-721.
MLA Luo, Qi,et al."Ganotheaecolin A, a Neurotrophic Conjugated Ergosterol with a Naphtho[1,8-ef]azulene Scaffold from Ganoderma theaecolum".ORGANIC LETTERS 19.3(2017):718-721.
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