| Antifungal Amide Alkaloids from the Aerial Parts of Piper flaviflorum and Piper sarmentosum | |
Shi, Yan-Ni1,2; Liu, Fang-Fang1,3; Jacob, Melissa R.4; Li, Xing-Cong4; Zhu, Hong-Tao1,5; Wang, Dong1,5 ; Cheng, Rong-Rong1; Yang, Chong-Ren1; Xu, Min1; Zhang, Ying-Jun1,5
| |
| 2017 | |
| Source Publication | PLANTA MEDICA
 |
| Volume | 83Issue:01-02Pages:143-150 |
| Abstract | Sixty-three amide alkaloids, including three new, piperflaviflorine A (1), piperflaviflorine B (2), and sarmentamide D (4), and two previously synthesized ones, (1E,3S)-1-cinnamoyl-3-hydroxypyrrolidine (3) and N-[7'-(4'-methoxyphenyl)ethyl]-2-methoxybenzamide (5), were isolated from the aerial parts of Piper flaviflorum and Piper sarmentosum. Their structures were elucidated by detailed spectroscopic analysis and, in case of 3, by single-crystal X-ray diffraction. Most of the isolates were tested for their antifungal and antibacterial activities. Ten amides (6-15) showed antifungal activity against Cryptococcus neoformans ATCC 90113 with IC50 values in the range between 4.7 and 20.0 mu g/mL. |
| Keyword | Piper Flaviflorum Piper Sarmentosum Piperaceae Amide Alkaloids Antifungal Activity |
| DOI | 10.1055/s-0042-109778 |
| Indexed By | SCI |
| Language | 英语 |
| WOS Research Area | Plant Sciences ; Pharmacology & Pharmacy ; Integrative & Complementary Medicine |
| WOS Subject | Plant Sciences ; Chemistry, Medicinal ; Integrative & Complementary Medicine ; Pharmacology & Pharmacy |
| WOS ID | WOS:000393182100018 |
| Citation statistics | |
| Document Type | 期刊论文 |
| Identifier | http://ir.kib.ac.cn/handle/151853/41890 |
| Collection | 植物化学与西部植物资源持续利用国家重点实验室 |
| Affiliation | 1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, 132 Lanhei Rd, Kunming 650201, Peoples R China 2.Univ Chinese Acad Sci, Beijing, Peoples R China 3.Yunnan Univ Tradit Chinese Med, Kunming, Peoples R China 4.Univ Mississippi, Sch Pharm, Pharmaceut Sci Res Inst, Natl Ctr Nat Prod Res, University, MS 38677 USA 5.Chinese Acad Sci, Kunming Inst Bot, Yunnan Key Lab Nat Med Chem, Kunming, Peoples R China |
| Recommended Citation GB/T 7714 | Shi, Yan-Ni,Liu, Fang-Fang,Jacob, Melissa R.,et al. Antifungal Amide Alkaloids from the Aerial Parts of Piper flaviflorum and Piper sarmentosum[J]. PLANTA MEDICA,2017,83(01-02):143-150. |
| APA | Shi, Yan-Ni.,Liu, Fang-Fang.,Jacob, Melissa R..,Li, Xing-Cong.,Zhu, Hong-Tao.,...&Zhang, Ying-Jun.(2017).Antifungal Amide Alkaloids from the Aerial Parts of Piper flaviflorum and Piper sarmentosum.PLANTA MEDICA,83(01-02),143-150. |
| MLA | Shi, Yan-Ni,et al."Antifungal Amide Alkaloids from the Aerial Parts of Piper flaviflorum and Piper sarmentosum".PLANTA MEDICA 83.01-02(2017):143-150. |
| Files in This Item: | Download All | |||||
| File Name/Size | DocType | Version | Access | License | ||
| s-0042-109778.pdf（212KB） | 期刊论文 | 作者接受稿 | 开放获取 | CC BY-NC-SA | View Download | |
Items in the repository are protected by copyright, with all rights reserved, unless otherwise indicated.
Edit Comment