| Antifungal Amide Alkaloids from the Aerial Parts of Piper flaviflorum and Piper sarmentosum | |
Shi, Yan-Ni1,2; Liu, Fang-Fang1,3; Jacob, Melissa R.4; Li, Xing-Cong4; Zhu, Hong-Tao1,5; Wang, Dong1,5 ; Cheng, Rong-Rong1; Yang, Chong-Ren1; Xu, Min1; Zhang, Ying-Jun1,5
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| 2017 | |
| 发表期刊 | PLANTA MEDICA
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| 卷号 | 83期号:01-02页码:143-150 |
| 摘要 | Sixty-three amide alkaloids, including three new, piperflaviflorine A (1), piperflaviflorine B (2), and sarmentamide D (4), and two previously synthesized ones, (1E,3S)-1-cinnamoyl-3-hydroxypyrrolidine (3) and N-[7'-(4'-methoxyphenyl)ethyl]-2-methoxybenzamide (5), were isolated from the aerial parts of Piper flaviflorum and Piper sarmentosum. Their structures were elucidated by detailed spectroscopic analysis and, in case of 3, by single-crystal X-ray diffraction. Most of the isolates were tested for their antifungal and antibacterial activities. Ten amides (6-15) showed antifungal activity against Cryptococcus neoformans ATCC 90113 with IC50 values in the range between 4.7 and 20.0 mu g/mL. |
| 关键词 | Piper Flaviflorum Piper Sarmentosum Piperaceae Amide Alkaloids Antifungal Activity |
| DOI | 10.1055/s-0042-109778 |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000393182100018 |
| 引用统计 | |
| 文献类型 | 期刊论文 |
| 条目标识符 | http://ir.kib.ac.cn/handle/151853/41890 |
| 专题 | 植物化学与西部植物资源持续利用国家重点实验室 |
| 作者单位 | 1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, 132 Lanhei Rd, Kunming 650201, Peoples R China 2.Univ Chinese Acad Sci, Beijing, Peoples R China 3.Yunnan Univ Tradit Chinese Med, Kunming, Peoples R China 4.Univ Mississippi, Sch Pharm, Pharmaceut Sci Res Inst, Natl Ctr Nat Prod Res, University, MS 38677 USA 5.Chinese Acad Sci, Kunming Inst Bot, Yunnan Key Lab Nat Med Chem, Kunming, Peoples R China |
| 推荐引用方式 GB/T 7714 | Shi, Yan-Ni,Liu, Fang-Fang,Jacob, Melissa R.,et al. Antifungal Amide Alkaloids from the Aerial Parts of Piper flaviflorum and Piper sarmentosum[J]. PLANTA MEDICA,2017,83(01-02):143-150. |
| APA | Shi, Yan-Ni.,Liu, Fang-Fang.,Jacob, Melissa R..,Li, Xing-Cong.,Zhu, Hong-Tao.,...&Zhang, Ying-Jun.(2017).Antifungal Amide Alkaloids from the Aerial Parts of Piper flaviflorum and Piper sarmentosum.PLANTA MEDICA,83(01-02),143-150. |
| MLA | Shi, Yan-Ni,et al."Antifungal Amide Alkaloids from the Aerial Parts of Piper flaviflorum and Piper sarmentosum".PLANTA MEDICA 83.01-02(2017):143-150. |
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| s-0042-109778.pdf（212KB） | 期刊论文 | 作者接受稿 | 开放获取 | CC BY-NC-SA | 浏览 下载 | |
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