Petchiethers A and B, novel meroterpenoids with a 14-or 15-membered ring from Ganoderma petchii
Li, Cheng-Gang1,2; Luo, Qi2,3; Guo, Ping-Xia2; Chen, Li-Li2; Cheng, Yong-Xian2
2016-12-01
发表期刊PHYTOCHEMISTRY LETTERS
卷号18期号:1页码:14-18
摘要Petchiethers A (1) and B (2), two novel meroterpenoids respectively with a 14- or 15-membered ring were isolated from the fruiting bodies of Ganoderma petchii. Their structures were identified by spectroscopic data. The absolute configurations of compounds 1 and 2 were assigned by computational methods. In particular, the stereochemistry of 1 was further confirmed by the Mosher's method. The inhibitory effects of compounds 1 and 2 on fibronectin secretion were evaluated by using the ELISA technique in TGF-beta 1-induced rat kidney tubular epithelial cells. The results show that these substances could inhibit fibronectin production in a dose-dependent manner, indicating their potential on kidney protection. (C) 2016 Published by Elsevier Ltd on behalf of Phytochemical Society of Europe.
关键词Meroterpenoids Petchiether a Petchiether b Absolute Configuration
DOI10.1016/j.phytol.2016.08.013
收录类别SCI
语种英语
WOS记录号WOS:000389521800004
引用统计
文献类型期刊论文
条目标识符http://ir.kib.ac.cn/handle/151853/33785
专题植物化学与西部植物资源持续利用国家重点实验室
作者单位1.Dali Univ, Coll Pharmaceut Sci, Dali 671002, Peoples R China
2.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West, Kunming 650201, Peoples R China
3.Univ Chinese Acad Sci, Yuquan Rd 19, Beijing 100049, Peoples R China
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GB/T 7714
Li, Cheng-Gang,Luo, Qi,Guo, Ping-Xia,et al. Petchiethers A and B, novel meroterpenoids with a 14-or 15-membered ring from Ganoderma petchii[J]. PHYTOCHEMISTRY LETTERS,2016,18(1):14-18.
APA Li, Cheng-Gang,Luo, Qi,Guo, Ping-Xia,Chen, Li-Li,&Cheng, Yong-Xian.(2016).Petchiethers A and B, novel meroterpenoids with a 14-or 15-membered ring from Ganoderma petchii.PHYTOCHEMISTRY LETTERS,18(1),14-18.
MLA Li, Cheng-Gang,et al."Petchiethers A and B, novel meroterpenoids with a 14-or 15-membered ring from Ganoderma petchii".PHYTOCHEMISTRY LETTERS 18.1(2016):14-18.
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