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题名: Absolute Configuration Determination of One New Compound Trichoderol A from Trichoderma sp Fungus
作者: Xu Lanlan1; Zhao Qiqi1; Yu He1, 2; Wang Jingchen1; Wang Huijun1; Yang Qin1; Zhu Huajie1; null(李艳)3
刊名: CHEMICAL JOURNAL OF CHINESE UNIVERSITIES-CHINESE
关键词: Trichoderma sp. ; Electronic circular dichroism ; Optical rotation ; Matrix ; Antibacterial activity
英文摘要: One new compound, trichoderol A (1), was isolated from cultures of the fungus Trichoderma sp. The structure of compound 1 was established by means of NMR and mass spectrometry. The absolute configuration (AC) was determined by means of comparing experimental electronic circular dichroism (ECD) and optical rotation (OR) of compound 1 with the calculated ECD and OR data of compound 1 using quantum methods, also using matrix model. Compound 1 was evaluated for antibacterial activities against three species of pathogenic bacteria, and the results showed that compound 1 had weak antibacterial activities (MIC = 25 mu mol/L).
出版日期: 2016-11-10
卷号: 37, 期号:11, 页码:1972-1976
DOI标识: 10.7503/cjcu20160499
语种: 英语
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内容类型: 期刊论文
URI标识: http://ir.kib.ac.cn/handle/151853/33766
Appears in Collections:植物化学与西部植物资源持续利用国家重点实验室_期刊论文

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作者单位: 1.Hebei Univ, Key Lab Med Chem & Mol Diag, Minist Educ, Key Lab Pharmaceut Qual Control Hebei Prov,Coll P, Baoding 071002, Peoples R China
2.Machinery Ind Analyt Ind Qual Supervis & Testing, Beijing 100095, Peoples R China
3.Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650204, Peoples R China

Recommended Citation:
Xu Lanlan,Zhao Qiqi,Yu He,et al. Absolute Configuration Determination of One New Compound Trichoderol A from Trichoderma sp Fungus[J]. CHEMICAL JOURNAL OF CHINESE UNIVERSITIES-CHINESE,2016,37(11):1972-1976.
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