Speramides A-B, two new prenylated indole alkaloids from the freshwater-derived fungus Aspergillus ochraceus KM007
Chang, Yao-Wen1,2,4; Yuan, Chun-Mao1,2; Zhang, Jing1,3; Liu, Shuai1,4; Cao, Pei1,4; Hua, Hui-Ming2; Di, Ying-Tong1,4; Hao, Xiao-Jiang1,4
2016-11-09
发表期刊TETRAHEDRON LETTERS
卷号57期号:45页码:4952-4955
摘要Two new prenylated indole alkaloids, named Speramides A (1) and B (2) were isolated from the extraction of the freshwater-derived fungus Aspergillus ochraceus KM007. Their structures were elucidated by means of spectroscopic analysis. Compound 1 is the first prenylated brevianamide derivative. These compounds isolated were evaluated for their antimicrobial activity, among which, compound 1 showed moderate activity against Pseudomonas aeruginosa with a MIC value of 0.8 mu M. (C) 2016 Published by Elsevier Ltd.
关键词Speramide Brevianamide Prenylated Indole Alkaloid Aspergillus Ochraceus Notoamide
资助信息National Natural Science Foundation of China(81573323); Science Foundation of Yunnan(2014A050); Technological Leading Talent Project of Yunnan(2015HA020); Young Academic and Technical Leader Raising Foundation of Yunnan Province; Xibuzhiguang Project
DOI10.1016/j.tetlet.2016.09.071
收录类别SCI
语种英语
WOS研究方向Chemistry
WOS类目Chemistry, Organic
WOS记录号WOS:000386403800002
引用统计
文献类型期刊论文
条目标识符http://ir.kib.ac.cn/handle/151853/33645
专题植物化学与西部植物资源持续利用国家重点实验室
作者单位1.Chinese Acad Sci, State Key Lab Phytochem & Plant Resources West Ch, Kunming Inst Bot, Kunming 650201, Yunnan, Peoples R China
2.Shenyang Pharmaceut Univ, Key Lab Struct Based Drug Design & Discovery, Minist Educ, Shenyang 110016, Liaoning, Peoples R China
3.Xinjiang Med Univ, Sch Chinese Tradit Med, 393 Xinyi Rd, Urumqi 830011, Xinjiang, Peoples R China
4.Yunnan Key Lab Nat Med Chem, Kunming 650201, Yunnan, Peoples R China
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Chang, Yao-Wen,Yuan, Chun-Mao,Zhang, Jing,et al. Speramides A-B, two new prenylated indole alkaloids from the freshwater-derived fungus Aspergillus ochraceus KM007[J]. TETRAHEDRON LETTERS,2016,57(45):4952-4955.
APA Chang, Yao-Wen.,Yuan, Chun-Mao.,Zhang, Jing.,Liu, Shuai.,Cao, Pei.,...&Hao, Xiao-Jiang.(2016).Speramides A-B, two new prenylated indole alkaloids from the freshwater-derived fungus Aspergillus ochraceus KM007.TETRAHEDRON LETTERS,57(45),4952-4955.
MLA Chang, Yao-Wen,et al."Speramides A-B, two new prenylated indole alkaloids from the freshwater-derived fungus Aspergillus ochraceus KM007".TETRAHEDRON LETTERS 57.45(2016):4952-4955.
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