Cytotoxicity of Triterpenoid Alkaloids from Buxus microphylla against Human Tumor Cell Lines

doi:10.3390/molecules21091125

	Cytotoxicity of Triterpenoid Alkaloids from Buxus microphylla against Human Tumor Cell Lines
	Bai, Shi-Tou 1,2; Zhu, Guo-Lei 1; Peng, Xing-Rong 1,3; Dong, Jin-Run 1,3; Yu, Mu-Yuan1 ; Chen, Jian-Chao 1,2,3; Wan, Luo-Sheng 1,3; Qiu, Ming-Hua1,2,3
	2016-09-01
发表期刊	MOLECULES
卷号	21 期号:9 页码:1
摘要	Three new triterpenoid alkaloids, namely buxmicrophyllines P-R (1-3), were isolated from the twigs and leaves of Buxusmicrophylla. Their structures were elucidated on the basis of NMR and MS spectroscopic analyses. Structurally, compounds 1-3 belong to the 9,10-cycloartane type alkaloids. In addition, compound 3 exhibited moderate cytotoxic activities in vitro against HL-60, SMMC-7221, A-549, MCF-7, and SW480 cell lines (with IC50 values ranging from 4.51 to 15.58 M).
关键词	Buxus Microphylla Triterpenoid Alkaloid Cytotoxicity
DOI	10.3390/molecules21091125
收录类别	SCI
语种	英语
WOS记录号	WOS:000385479800022
引用统计
文献类型	期刊论文
条目标识符	http://ir.kib.ac.cn/handle/151853/33623
专题	植物化学与西部植物资源持续利用国家重点实验室
作者单位	1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Peoples R China 2.Yunnan Univ Tradit Chinese Med, Sch Tradit Chinese Med, Kunming 650500, Peoples R China 3.Chinese Acad Sci, Kunming Inst Bot, Yunnan Key Lab Nat Med Chem, Kunming 650201, Peoples R China
推荐引用方式 GB/T 7714	Bai, Shi-Tou,Zhu, Guo-Lei,Peng, Xing-Rong,et al. Cytotoxicity of Triterpenoid Alkaloids from Buxus microphylla against Human Tumor Cell Lines[J]. MOLECULES,2016,21(9):1.
APA	Bai, Shi-Tou.,Zhu, Guo-Lei.,Peng, Xing-Rong.,Dong, Jin-Run.,Yu, Mu-Yuan.,...&Qiu, Ming-Hua.(2016).Cytotoxicity of Triterpenoid Alkaloids from Buxus microphylla against Human Tumor Cell Lines.MOLECULES,21(9),1.
MLA	Bai, Shi-Tou,et al."Cytotoxicity of Triterpenoid Alkaloids from Buxus microphylla against Human Tumor Cell Lines".MOLECULES 21.9(2016):1.

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