Vibsanin B衍生物及其药物组合物和其在制药中的应用
赵勤实; 陈竺; 陈赛娟; 夏成峰; 邵立东; 叶柏新
2015-05-18
Date Available2016-01-13
Abstract式(I)所示的Vibsanin?B衍生物及其药用盐,其制备方法,以其为有效成分的药物组合物,它们在制备治疗或预防肝癌、白血病、结肠癌、乳腺癌及肺癌等癌症药物中的应用。本发明Vibsanin?B衍生物对以上肿瘤株的生长的半数抑制浓度(IC50)在2.64-3.46μM之间,通过在C18位氢键作用的变动,能显著提高Vibsanin?B的抗肿瘤活性。
Document Type专利
Identifierhttp://ir.kib.ac.cn/handle/151853/28650
Collection植物化学与西部植物资源持续利用国家重点实验室
Recommended Citation
GB/T 7714
赵勤实,陈竺,陈赛娟,等. Vibsanin B衍生物及其药物组合物和其在制药中的应用. CN201510253240.7[P]. 2015-05-18.
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